Alexander B Sigalov

Principal investigator.

BiotechORCID
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2015First federal award
$5.9MFederal grants as PI11 awards
5Patents grantedLatest Dec 17, 2024
87Papers1,667 citations
Career record

Federal awards and patents by year

20152026
AwardsPatents
Federal awards as principal investigator

11 awards · $5.9M

DateAgencyAwardAmountCompany
Sep 4, 2026NIHSBIR Phase I
New TREM-1 therapy for inflammatory bowel disease
$353KSIGNABLOK, INC.
May 13, 2026NIHSBIR Phase II
First-in-class TREM-1 inhibitors for neovascular retinal diseases
$830KSIGNABLOK, INC.
Sep 10, 2025NIHSBIR Phase I
TREM-1 therapy for the treatment of empyema
$458KSIGNABLOK, INC.
Apr 7, 2025NIHSBIR Phase II
First-in-class TREM-1 inhibitors for neovascular retinal diseases
$830KSIGNABLOK, INC.
Sep 6, 2023NIHSBIR Phase II
First-in-class TREM-1 inhibitors for neovascular retinal diseases
$278KSIGNABLOK, INC.
Jul 31, 2023NIHSBIR Phase I
New mechanism-based TREM-1 therapy for acute respiratory distress syndrome
$273KSIGNABLOK, INC.
Sep 4, 2020NIHSBIR Phase II
First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer
$1.2MSIGNABLOK, INC.
Sep 25, 2019NIHSBIR Phase II
First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer
$800KSIGNABLOK, INC.
Aug 13, 2019NIHSBIR Phase I
First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer
$2KSIGNABLOK, INC.
Sep 21, 2017NIHSBIR Phase I
First-in-class TREM-1 inhibitors in combination therapy for pancreatic cancer
$225KSIGNABLOK, INC.
Jun 8, 2015NIHSBIR Phase II
Multifunctional nanoformulations for diagnostic imaging of atherosclerosis
$673KSIGNABLOK, INC.
Patents

6 patents as inventor

Matched by the first inventor’s name and the patent’s company.

Among 4,078 researchers in Biotech

Peer ranks

Federal funding#199
Awards as PI#106
Patents#25
From filings, awards and patents

Companies

Federal awards through Oct 21, 2026 and patents through Oct 20, 2026. Awards come from NIH, NSF and other agency records that name a principal investigator; DoD and NASA contract awards do not, so they are not shown here. Researchers are matched by name and company.