Upstream Biotechnology, Inc.

NC · Agritech · Private

Genetic trait enabling rapid pathogen response in plants for disease resistance

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Updated

Sector
Agritech
Headquarters
NC
Latest Form D
$625K, Sep 2025
Total capital
$1.8M
Federal grants
$1.2M
2 awards · 2019–2022
Rank in peer group#21 of 27
Private capital raised
$625K
1 Form D · last Sep 2025
13 months since last filing
Federal contracts
None on recordNo federal contract awards found.
Granted patents
None on recordNo USPTO grants. Applications publish after 18 months.

Capital timeline

2019202020212022202320242025FEDERAL ↑EQUITY ↓Cumulative $1.8M$225K$995K1st Form D$625K
2019202120232025FEDERAL ↑EQUITY ↓Cumulative $1.8M$225K$995K1st Form D$625K

Latest events

  • Private capital raisedForm D · SEC · 1st filing$625K
  • Federal grantNSF · Phase II · SBIR Phase II: Engineering broad-spectrum disease resistance in soybean without fitness cost$995K
  • Federal grantNSF · Phase I · SBIR Phase I: Engineering broad-spectrum disease resistance in soybean without fitness cost$225K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Federal first

80months

from Upstream Biotechnology, Inc.’s first federal award to its first private round.

First federal award · Feb 2019
NSF · $225K
First Form D · Sep 2025
$625K · 1st Form D
Awards before first raise
2 awards

An association in public records, not a cause or a prediction.

Standing among 27 peers

Line = median

Agritech · Molecule

  • Federal grantsBelow median

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants
  • George H. GreeneResearcherExecutive Officer, DirectorLinked by $995K in grants as PI
  • George H. GreeneResearcherExecutive Officer, DirectorLinked by $995K in grants as PI
  • Karen LeVertDirectorNamed in SEC Form D filings
  • Xiao-fang WangDirectorNamed in SEC Form D filings
  • Xinnian DongDirectorNamed in SEC Form D filings

What it has protected

No granted patents are on record.

USPTO usually publishes applications 18 months after filing, so recent applications may not be visible yet. Patents assigned under a different entity name won’t match.

Checked: USPTO granted patents and published applications · Oct 23, 2026

  • UPSTREAM BIOTECHNOLOGY INCShares a founder: Peter Alexander
  • Ceres Tag LtdSimilar federal contract value in Agritech · null in contracts
  • GROGURU, INC.Similar federal contract value in Agritech · null in contracts
  • CLARUS LABS LLCSimilar federal contract value in Agritech · null in contracts
  • Flexterra, Inc.Similar federal contract value in Agritech · null in contracts
  • APPLIED LIFESCIENCES & SYSTEMS POULTRY, INC.Similar federal contract value in Agritech · null in contracts

Regulatory activity · Agritech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .