Twist Bioscience
Silicon-based DNA synthesis platform and synthetic DNA tools including gene synthesis, oligo pools, and NGS reagents
- Sector
- Biotech
- Headquarters
- SAN FRANCISCO, CA
- Founded
- 2013
- Latest Form D
- $50M, Apr 2018
- Total capital
- $226M
- Federal grants
- None on recordNo awards found in SBIR/STTR, NIH, NSF or DoD records.
- Private capital raised
- $214M
- 7 Form D · last Apr 2018
- 103 months since last filing
- Federal contracts
- $12M
- 38 awards · Defense, Health and Human S, Veterans Affairs
- Rank in Biotech#57 of 4373
- Granted patents
- 22
- 18 pending · first 2025
- Rank in peer group#3 of 342
Capital timeline
Latest events
- Federal contractHealth and Human S · The Purpose Of This Purchase Order Is To Provide The National Institute Of Environmental Health Sciences / Division Of Translational Toxicology (dtt) / Mechanistic Toxicology Branch / Mitochondrial Toxicology And Biology Group With Twist Biosciences$27K
- Federal contractVeterans Affairs · Methylome Sample Processing Services For The Va Long Beach Research Service.$47K
- Federal contractJustice · Twist Bioscience Equipment$97K
- Federal contractAgriculture · Twist 96-PLEX Library Prep Kit 10X96 Samples$61K
- Federal contractHealth and Human S · Biological And Reagent Materials$12K
- Federal contractVeterans Affairs · Shahrara Humanized Monoclonal Antibody For Syndecan Twist Bioscience$105K
- Federal contractHealth and Human S · Lap Supplies$157K
- Private capital raisedForm D · SEC · 7th filing$50M
- Private capital raisedForm D · SEC · 6th filing$32.2M
- Private capital raisedForm D · SEC · 5th filing$2.6M
- Private capital raisedForm D · SEC · 4th filing$61M
- Private capital raisedForm D · SEC · 3rd filing$37M
- Private capital raisedForm D · SEC · 2nd filing$26M
- Private capital raisedForm D · SEC · 1st filing$4.7M
Show 30 earlier federal awards
- Federal contractHealth and Human S · Generation Of A Saturation Mutagenesis Cdna Library Of PINK1 Cdna$23K
- Federal contractHealth and Human S · Oligos Pools Are Needed For A Gene Expression/ Mpra Project$22K
- Federal contractHealth and Human S · Dr. Laura Elnitski Lab Need The Twist Custom Capture Panel For A New Blood Based Cancer Diagnostic To Detect HHV8 In Plasma Of Hiv PATIENTS.[24-004752]$14K
- Federal contractHealth and Human S · Niddk / Twist Library Preparation Kit 1,$15K
- Federal contractHealth and Human S · Dna Synthesis Services For Gene Cloning$22K
- Federal contractVeterans Affairs · Ffpe Sampling$64K
- Federal contractHealth and Human S · Custom Single Site Variant Library$24K
- Federal contractVeterans Affairs · Methylome Sequencing$48K
- Federal contractHealth and Human S · Twist Rna For FLUSC2 Multiple$51K
- Federal contractHealth and Human S · Clonal Genes$14K
- Federal contractHealth and Human S · Custom Cloned Pooled Oligo Library$78K
- Federal contractDefense · Twist Research Panels$18K
- Federal contractHealth and Human S · Twist Custom Panel Hybrid Probes$15K
- Federal contractHealth and Human S · Oligo Pools$60K
- Federal contractHealth and Human S · Cloned Oligo Pool Libraries$26K
- Federal contractHealth and Human S · Oligo$14K
- Federal contractHealth and Human S · Custom Oligo Library$12K
- Federal contractHealth and Human S · Radx Tech Project 6818 Portable, Rapid, Disposable Test With Synthetic Antibodies For Testing Anywhere$5M
- Federal contractHealth and Human S · SC2 Positive Control Synthetic Rna Control Material$540K
- Federal contractHealth and Human S · SC2 Positive Control Synthetic Rna Control$264K
- Federal contractHealth and Human S · Custom Oligo Library$21K
- Federal contractHealth and Human S · Sars COV2 Rna Control$126K
- Federal contractHealth and Human S · Sars Cov 2 Rna Controls$220K
- Federal contractHealth and Human S · Twist Bioscience CORPORATION:1278803 [20-006609]$24K
- Federal contractHealth and Human S · Covid Dna Contructs$98K
- Federal contractHealth and Human S · Sars CO-V-2 Rna Controls$82K
- Federal contractHealth and Human S · COVID-19 Dna Constructs$30K
- Federal contractHealth and Human S · Twist Bioscience CORPORATION:1278803 [18-022534]$4K
- Federal contractHealth and Human S · Twist Bioscience CORPORATION:1278803 [17-061421]$5K
- Federal contractDefense · Living Foundries: 1000 Molecules TA1. Darpa's Living Foundries: 1000 Molecules Program Seeks To Build A Scalable, Integrated, Rapid Design And Prototyping Infrastructure For The Facile Engineering Of Biology. This Effort Is An Advanced Study. The Twist Effort Proposes To Develop A Large Scale, High-throughput Platform For Constructing Low-cost Genetic Designs.$4.5M
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
1 record has no date or no amount, so it isn’t placed on the timeline.
Standing among 342 peers
Line = medianBiotech · Platform
- Granted patents#3 · top 1%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
From SEC Form D filings- Bill James PeckExecutive Officer, PromoterNamed in SEC Form D filings
- Bob Marine RagusaDirectorNamed in SEC Form D filings
- Emily Marine LeproustExecutive Officer, Director, PromoterNamed in SEC Form D filings
- Fred Marine CravesDirectorNamed in SEC Form D filings
- Keith Marine CrandellDirectorNamed in SEC Form D filings
- Minqi Marine LiDirectorNamed in SEC Form D filings
Show all 11 people
- Nick James NaclerioDirectorNamed in SEC Form D filings
- Paul James ConleyDirectorNamed in SEC Form D filings
- Rob Marine ChessDirectorNamed in SEC Form D filings
- Solange James GlaizeExecutive OfficerNamed in SEC Form D filings
- William Charles BanyaiExecutive Officer, DirectorNamed in SEC Form D filings
What it has protected
USPTO · 22 granted of 40- GrantedMethods And Compositions For High Throughput Sample Preparation Using Double Unique Dual IndexingUSPTOUS 12,742,194
- PendingPolynucleotides, Reagents, And Methods For Nucleic Acid HybridizationUSPTOApplication 19409038
- GrantedMethods And Compositions Relating To Continuous SequencingUSPTOUS 12,716,093
Show all 40 patent records
- Methods And Compositions For High Throughput Sample Preparation Using Double Unique Dual IndexingSep 22, 2026 · US 12,742,194Granted
- Polynucleotides, Reagents, And Methods For Nucleic Acid HybridizationSep 3, 2026 · Application 19409038Pending
- Methods And Compositions Relating To Continuous SequencingAug 25, 2026 · US 12,716,093Granted
- Methods For Polynucleotide SynthesisAug 4, 2026 · US 12,697,597Granted
- Electrochemical Polynucleotide SynthesisJul 23, 2026 · Application 19451765Pending
- Methods And Compositions For Rapid Nucleic Library PreparationJul 21, 2026 · US 12,686,863Granted
- Variant Nucleic Acid Libraries For TigitJul 2, 2026 · Application 19113912Pending
- Libraries For Rna EnrichmentJul 2, 2026 · Application 19116608Pending
- Compositions And Methods For Multiplex Nucleic Acids SynthesisJun 30, 2026 · US 12,668,791Granted
- Hybridization Methods And ReagentsJun 25, 2026 · Application 19092784Pending
- Methylation-mediated Adapter Removal On Nucleic Acid SequencesJun 2, 2026 · US 12,644,115Granted
- De Novo Synthesized Gene LibrariesMay 21, 2026 · Application 19456767Pending
- Polynucleotide Libraries Having Controlled Stoichiometry And Synthesis ThereofMay 14, 2026 · Application 19298873Pending
- Methods And Compositions For Genomic AnalysisApr 30, 2026 · Application 19116775Pending
- Methods And Compositions Relating To Covalently Closed Nucleic AcidsMar 10, 2026 · US 12,571,024Granted
- Antibodies That Bind Adenosine A2A Receptors And Methods Of Use Thereof To Treat Cancer And Neurological DiseasesMar 10, 2026 · US 12,570,750Granted
- De Novo Synthesized Gene LibrariesMar 10, 2026 · US 12,569,822Granted
- Variant Nucleic Acid Libraries For Antibody OptimizationMar 3, 2026 · US 12,565,715Granted
- Variant Nucleic Acid Libraries For GlycansFeb 17, 2026 · US 12,553,151Granted
- Devices And Methods For SynthesisJan 27, 2026 · US 12,534,494Granted
- Polynucleotides, Reagents, And Methods For Nucleic Acid HybridizationJan 13, 2026 · US 12,522,868Granted
- Variant Nucleic Acid Libraries For Mast CellsJan 1, 2026 · Application 19308657Pending
- Substrate Cleavage For Nucleic Acid SynthesisDec 4, 2025 · Application 18854437Pending
- Highly Accurate De Novo Polynucleotide SynthesisNov 20, 2025 · Application 19233645Pending
- Methods and Compositions Relating to GLP1R VariantsNov 6, 2025 · Application 19276502Pending
- Antibodies That Bind GLP1RAug 28, 2025 · Application 19207949Pending
- Methods And Compositions Relating To GLP1R VariantsAug 19, 2025 · US 12,391,762Granted
- Highly Accurate De Novo Polynucleotide SynthesisJul 15, 2025 · US 12,357,959Granted
- Antibodies That Bind GLP1RJun 17, 2025 · US 12,331,427Granted
- Libraries For Next Generation SequencingJun 12, 2025 · Application 18980172Pending
- Bispecific SARS-COV-2 Antibodies And Methods Of UseJun 10, 2025 · US 12,325,739Granted
- Variant Nucleic Acid Libraries For CoronavirusMay 20, 2025 · US 12,304,965Granted
- Methods For Seamless Nucleic Acid AssemblyMay 15, 2025 · Application 19029966Pending
- Antibodies that Bind TIGITMay 8, 2025 · Application 18932757Pending
- Methods and Compositions Relating to Adenosine ReceptorsMay 8, 2025 · Application 18975629Pending
- Methods For Seamless Nucleic Acid AssemblyApr 8, 2025 · US 12,270,028Granted
- Antibodies That Bind CD3 EpsilonMar 25, 2025 · US 12,258,406Granted
- Dickkopf-1 Variant Antibodies and Methods of UseMar 6, 2025 · Application 18902114Pending
- Methods And Compositions Relating To Covid Antibody EpitopesJan 21, 2025 · US 12,201,857Granted
- Methods And Compositions Relating To Adenosine ReceptorsJan 21, 2025 · US 12,202,905Granted
Related companies, and why
- INIMMUNE CORPSimilar federal contract value in Biotech · $12.8M in contracts
- ZATA PHARMACEUTICALS, INC.Similar federal contract value in Biotech · $12.6M in contracts
- INOVIO PHARMACEUTICALS, INC.Similar federal contract value in Biotech · $12M in contracts
- Codagenix Inc.Similar federal contract value in Biotech · $11.2M in contracts
- Ceramedix Holding, LLCSimilar federal contract value in Biotech · $10.2M in contracts
- SACHI BIOWORKS, INC.Similar federal contract value in Biotech · $9.8M in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .