TVARDI THERAPEUTICS, INC.
Small-molecule STAT3 inhibitor (C188-9) for treating chronic kidney disease-induced muscle wasting
- Sector
- Biotech
- Headquarters
- HOUSTON, TX
- Founded
- 2017
- Latest Form D
- $72.4M, Jun 2021
- Total capital
- $76.9M
- Federal grants
- $1.3M
- 1 award · 2018
- Rank in peer group#226 of 326
- Private capital raised
- $75.6M
- 2 Form D · last Jun 2021
- 64 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 4
- 20 pending · first 2021
- Rank in peer group#35 of 326
Capital timeline
Latest events
- Private capital raisedForm D · SEC · 2nd filing$72.4M
- Federal grantHealth and Human S · Phase II · Oral Small Molecule STAT3 Inhibitor to Treat Cachexia in Chronic Kidney Disease$1.3M
- Private capital raisedForm D · SEC · 1st filing$3.1M
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 326 peers
Line = medianBiotech · Molecule
- Federal grantsBelow median
- Granted patents#35 · top 11%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Imran AlibhaiResearcherExecutive Officer, DirectorLinked by 4 patents
- David J. TweardyExecutive Officer, DirectorNamed in SEC Form D filings
- Jamie McNabDirectorNamed in SEC Form D filings
- Michael WyzgaDirectorNamed in SEC Form D filings
- Ronald J. DePinhoDirectorNamed in SEC Form D filings
- Sujal ShahDirectorNamed in SEC Form D filings
Show all 7 people
- Wallace HallDirectorNamed in SEC Form D filings
What it has protected
USPTO · 4 granted of 24- GrantedTherapeutic Compounds, Formulations, And Uses ThereofUSPTOUS 12,053,444
- GrantedProdrugs Of STAT3 InhibitorsUSPTOUS 12,043,640
- PendingTherapeutic Compounds For Methods Of Use In Insulin ResistanceUSPTOApplication 17781349
Show all 24 patent records
- Therapeutic Compounds, Formulations, And Uses ThereofAug 6, 2024 · US 12,053,444Granted
- Prodrugs Of STAT3 InhibitorsJul 23, 2024 · US 12,043,640Granted
- Therapeutic Compounds For Methods Of Use In Insulin ResistanceMar 9, 2023 · Application 17781349Pending
- Therapeutic Compounds, Formulations, And Uses ThereofJan 10, 2023 · US 11,547,683Granted
- Therapeutic Compounds, Formulations, And Uses ThereofAug 3, 2021 · US 11,077,077Granted
- Therapeutic Compounds, Formulations, And Use ThereofApplication PCTUS2023070440Pending
- Prodrugs Of STAT3 InhibitorsApplication PCTUS2023068240Pending
- Combination Therapy And Uses ThereofApplication PCTUS2023063701Pending
- Therapeutic Compounds, Formulations, And Use ThereofApplication PCTUS2023063520Pending
- STAT3 Inhibitors For Use In The Treatment Of CancerApplication 63387069Pending
- Therapeutic Compounds, Formulations, And Use ThereofApplication 63369055Pending
- Prodrugs Of STAT3 InhibitorsApplication 63366437Pending
- Combination Therapy And Uses ThereofApplication 63268897Pending
- Therapeutic Compounds, Formulations, And Use ThereofApplication 63268723Pending
- Therapeutic Compounds, Formulations, And Uses ThereofApplication PCTUS2021014642Pending
- Therapeutic Compounds For Methods Of Use In Insulin ResistanceApplication PCTUS2020063167Pending
- Therapeutic Compounds, Formulations, And Uses ThereofApplication 62965738Pending
- STAT3 InhibitorsApplication PCTUS2019028135Pending
- STAT3 InhibitorsApplication 62793491Pending
- STAT3 InhibitorsApplication 62659872Pending
- STAT3 Inhibitors For Use In The Treatment Of CancerApplication 63559468Pending
- Solid-state Forms Of STAT3 Inhibitors And Methods Of Use ThereofApplication 63612879Pending
- STAT3 Inhibitors For Use In The Treatment Of CancerApplication PCTUS2023083440Pending
- Formulations Of STAT3 Inhibitors And Methods Of Use ThereofApplication 63580555Pending
Related companies, and why
- Entact Bio, Inc.Similar federal contract value in Biotech · null in contracts
- CIRC Biosciences, Inc.Similar federal contract value in Biotech · null in contracts
- HGG RESEARCH, LLCSimilar federal contract value in Biotech · null in contracts
- Bambusa TherapeuticsSimilar federal contract value in Biotech · null in contracts
- IMMUNOMATICS, INC.Similar federal contract value in Biotech · null in contracts
- Secura Bio Holdings, Inc.Similar federal contract value in Biotech · null in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .