SYNTHONICS, INC.
A controlled-release oral formulation of liothyronine (T3) using metallo-T3 complexes to achieve sustained thyroid hormone delivery
- Sector
- Medtech
- Headquarters
- BLACKSBURG, VA
- Founded
- 2006
- Latest Form D
- $500K, Jul 2014
- Total capital
- $5.7M
- Federal grants
- $2.2M
- 4 awards · 2015–2020
- Rank in peer group#40 of 41
- Private capital raised
- $3.5M
- 3 Form D · last Jul 2014
- 147 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 2
- 10 pending · first 2017
- Rank in peer group#9 of 41
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · Proof of Extended Absorption of Liothyronine from PolyZincLiothyronine (PZL) inHumans$1M
- Federal grantHealth and Human S · Phase II · Proof of Extended Absorption of Liothyronine from PolyZincLiothyronine (PZL) inHumans$971K
- Federal grantHealth and Human S · Phase I · Poly-Metallo-Liothyronine Complexes for Hypothyroidism Treatment$221K
- Federal grantHealth and Human S · Phase II · Levodopa Pharmacokinetic Optimization by Metal Coordination$5K
- Private capital raisedForm D · SEC · 3rd filing$500K
- Private capital raisedForm D · SEC · 2nd filing$355K
- Private capital raisedForm D · SEC · 1st filing$2.6M
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 41 peers
Line = medianMedtech · Molecule
- Federal grantsBelow median
- Granted patents#9 · top 22%
- Linked publications#8 · top 20%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- thomas j piccarielloResearcherExecutive Officer, DirectorLinked by 1 patent · $2.2M in grants as PI
- john j borlingDirectorNamed in SEC Form D filings
- john j tinkhamExecutive Officer, DirectorNamed in SEC Form D filings
- kenneth j slepickaExecutive Officer, DirectorNamed in SEC Form D filings
- scott j palmerDirectorNamed in SEC Form D filings
What it has protected
USPTO · 2 granted of 12- PendingMetallo-liothyronineUSPTOApplication 18362813
- GrantedMetallo-liothyronineUSPTOUS 11,712,426
- PendingSolid Micellar Compositions Of Cannabinoid AcidsUSPTOApplication 17423846
Show all 12 patent records
- Metallo-liothyronineNov 30, 2023 · Application 18362813Pending
- Metallo-liothyronineAug 1, 2023 · US 11,712,426Granted
- Solid Micellar Compositions Of Cannabinoid AcidsMar 17, 2022 · Application 17423846Pending
- Coordination Complexes, Pharmaceutical Solutions Comprising Coordination Complexes, And Methods Of Treating PatientsJul 20, 2017 · Application 15476533Pending
- Coordination Complexes, Pharmaceutical Solutions Comprising Coordination Complexes, And Methods Of Treating PatientsApr 18, 2017 · US 9,624,256Granted
- Metal Coordinated CompositionsMar 19, 2015 · Application 14547803Pending
- Metal Coordinated CompositionsJul 18, 2013 · Application 13786123Pending
- Coordination Complexes, Pharmaceutical Solutions Comprising Coordination Complexes, And Methods Of Treating PatientsApplication PCTUS2011037144Pending
- Frequency Modulated Drug Delivery (fmdd)Application PCTUS2009067136Pending
- Metal Coordinated CompositionsApplication PCTUS2006031757Pending
- Bismuth-containing Compounds, Coordination Polymers, Methods For Modulating Pharmacokinetic Properties Of Biologically Active Agents, And Methods For Treating PatientsApplication PCTUS2011059753Pending
- Solid Micellar Compositions Of Cannabinoid AcidsApplication PCTUS2020014109Pending
Recent research by its founders
- Sustained Release T3 Therapy: Animal Models and Translational Applications201931 cites
- Isolation, Structure, Synthesis, and Bioactivity of a Novel Putative Insulin Mediator. A Galactosamine chiro-Inositol Pseudo-Disaccharide Mn<sup>2+</sup> Chelate with Insulin-like Activity200369 cites
- Studies relating to fecapentaene-1219890 cites
Related companies, and why
- SENSORIIS INCSimilar federal contract value in Medtech · null in contracts
- CORDANCE MEDICAL, INC.Similar federal contract value in Medtech · null in contracts
- Kepley Biosystems IncorporatedSimilar federal contract value in Medtech · null in contracts
- HAEMATOLOGIC TECHNOLOGIES, INC.Similar federal contract value in Medtech · null in contracts
- IMOL RADIOPHARMACEUTICALS, LLCSimilar federal contract value in Medtech · null in contracts
- Asante Bio LLCSimilar federal contract value in Medtech · null in contracts
Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .