SIMULATIONS PLUS, INC.

Biotech · Public

Software algorithm that performs 3D ligand shape matching for drug discovery by accounting for water molecules in protein-ligand binding pockets

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Updated Oct 23, 2026

Sector: Biotech
Total capital: $2.3M

Federal grants: $2.1M; 4 awards · 2021–2024; Rank in peer group#19 of 19
Private capital raised: None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
Federal contracts: $136K; 3 awards · Health and Human S, Environmental Prot; Rank in Biotech#316 of 4373
Granted patents: 0; 1 pending

Capital timeline

Latest events

Sep 2024Federal grantHealth and Human S · Phase I · Improving Similarity Scoring in Drug Discovery: Solving by Solvating$307K
May 2023Federal grantHealth and Human S · Phase II · Software for predicting liver injury from biologics drug candidates using data from a human liver microphysiology system$834K
Feb 2022Federal grantHealth and Human S · Phase II · Software for predicting liver injury from biologics drug candidates using data from a human liver microphysiology system$863K
Nov 2021Federal grantHealth and Human S · Phase I · Software for Predicting Liver Injury from Biologics Drug Candidates Using Data from a Human Liver Microphysiology System$145K
Jul 2015Federal contractHealth and Human S · Igf::ot::igf Annual License Renewal Of Simulations Plus Software - User: James Peggins$12K
Jun 2015Federal contractEnvironmental Prot · Gastroplus And Admet Predictor Software Renewal, Tan Igf::ot::igf$3K
Aug 2012Federal contractHealth and Human S · Other Functions-gastroplus Software$121K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing among 19 peers

Line = median

Biotech · Software

Federal grantsBelow median

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

No founders are linked to this company yet.

Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.

Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026

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What it has protected

USPTO · 0 granted of 1

PendingSimulation-based Dynamic Risk StratificationUSPTOApplication 63446560

HAGER BIOSCIENCES, LLCSimilar federal contract value in Biotech · $142K in contracts
INSMED INCSimilar federal contract value in Biotech · $139K in contracts
ATLASXOMICS INCSimilar federal contract value in Biotech · $137K in contracts
NEUROSETTA LLCSimilar federal contract value in Biotech · $135K in contracts
Corcept TherapeuticsSimilar federal contract value in Biotech · $132K in contracts
Akcea TherapeuticsSimilar federal contract value in Biotech · $129K in contracts

Regulatory activity · Biotech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.