SIGNUM BIOSCIENCES
Topical isoprenylcysteine anti-inflammatory molecules (SIG1451, SIG1456) for atopic dermatitis treatment
- Sector
- Biotech
- Headquarters
- MONMOUTH JUNCTION, NJ
- Latest Form D
- $4M, Jul 2011
- Total capital
- $7M
- Federal grants
- $3M
- 3 awards · 2017–2019
- Rank in peer group#341 of 514
- Private capital raised
- $4M
- 1 Form D · last Jul 2011
- 183 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 10
- 24 pending · first 2017
- Rank in peer group#29 of 514
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · A Topical Non-steroidal Anti-inflammatory for Atopic Dermatitis$778K
- Federal grantHealth and Human S · Phase II · A Topical Non-steroidal Anti-inflammatory for Atopic Dermatitis$1.1M
- Federal grantHealth and Human S · Phase II · A Topical Non-steroidal Anti-inflammatory for Atopic Dermatitis$1.1M
- Private capital raisedForm D · SEC · 1st filing$4M
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 514 peers
Line = medianBiotech · Molecule
- Federal grantsBelow median
- Granted patents#29 · top 6%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Jeffry StockResearcherDirectorLinked by 4 patents
- Braham ShrootDirectorNamed in SEC Form D filings
- Gregory StockDirectorNamed in SEC Form D filings
- Kunio YamadaDirectorNamed in SEC Form D filings
- Stephen ModzelewskiDirectorNamed in SEC Form D filings
What it has protected
USPTO · 10 granted of 34- GrantedCompositions Derived From Salvia Hispanica SeedsUSPTOUS 12,599,642
- GrantedCompounds And Methods Of UseUSPTOUS 11,802,107
- GrantedCompounds And Methods Of UseUSPTOUS 11,518,738
Show all 34 patent records
- Compositions Derived From Salvia Hispanica SeedsApr 14, 2026 · US 12,599,642Granted
- Compounds And Methods Of UseOct 31, 2023 · US 11,802,107Granted
- Compounds And Methods Of UseDec 6, 2022 · US 11,518,738Granted
- Compounds And Methods Of UseApr 13, 2021 · US 10,975,023Granted
- Methods For Preparing Botanical ExtractsFeb 9, 2021 · US 10,912,812Granted
- Pharmaceutical Formulations And Their UseJun 11, 2020 · Application 16324045Pending
- Compounds, Compositions And Methods For Making The SameMar 10, 2020 · US 10,583,119Granted
- Tryptamide Compositions And Methods Of UseJun 11, 2019 · US 10,314,817Granted
- Isoprenyl Compounds And Methods ThereofJun 11, 2019 · US 10,314,802Granted
- Pharmaceutical Formulations And Their UseJun 6, 2019 · Application 16323970Pending
- Use Of Anti-bacterial Agents For The Treatment Of Epithelial-related ConditionsNov 6, 2018 · US 10,117,904Granted
- Isoprenyl Compounds and Methods ThereofAug 29, 2017 · US 9,744,147Granted
- Natural Extracts For Modulating PP2A Methylation, And Providing Antioxidant And Anti Inflammatory ActivityAug 10, 2017 · Application 15327875Pending
- Compounds And Methods UseApplication PCTUS2018013650Pending
- Compositions Derived From Salvia Hispanica SeedsApplication 62984960Pending
- Formulations For Increasing Gene ExpressionApplication PCTUS2016057316Pending
- Compositions Derived From Salvia Hispanica SeedsApplication PCTUS2021020830Pending
- Tryptamaide Compositions And Methods Of UseApplication PCTUS2015055745Pending
- Tryptamide Compositions and Methods of UseApplication 62121711Pending
- Tryptamide Compositions and Methods of UseApplication 62063983Pending
- Use Of Anti-bacterial Agents For The Treatment Of Epithelial-related ConditionsApplication PCTUS2010056624Pending
- Anti-inflammatory ComplexesApplication PCTUS2010021544Pending
- Isoprenyl Compounds And Methods ThereofApplication PCTUS2009064077Pending
- Compounds, Compositions And Methods For Making The SameApplication PCTUS2009041321Pending
- Topical Compositions And Methods Utilizing Peptides Containing Lipid-modified Cysteine-containing PeptidesApplication PCTUS2009035162Pending
- Acetyl Mimic Compounds For The Inhibition Of Isoprenyl-s-cysteinyl MethyltransferaseApplication PCTUS2009034120Pending
- Improved Method For Preparing Isoprenyl Cysteine Compounds And Analogs ThereofApplication PCTUS2009031828Pending
- Acid Mimic Compounds For The Inhibition Of Isoprenyl-s-cysteinyl MethyltransferaseApplication PCTUS2008085274Pending
- Compositions And Methods For Treating Inflammatory ConditionsApplication PCTUS2006023022Pending
- Compositions And Methods For Enhancing Cognitive FunctionApplication PCTUS2006003686Pending
- Topical Compositions And Methods For Epithelial-related ConditionsApplication PCTUS2005020555Pending
- Pharmaceutical Formulations And Their UseApplication PCTUS2017045625Pending
- Modulatio Of Protein Methylation And Phosphoprotein PhosphateApplication PCTUS2003007658Pending
- Pharmaceutical Formulations And Their UseApplication PCTUS2017045945Pending
Related companies, and why
- T3D Therapeutics, Inc.Similar federal contract value in Biotech · null in contracts
- Novosteo Inc.Similar federal contract value in Biotech · null in contracts
- Everest Biolabs, Inc.Similar federal contract value in Biotech · null in contracts
- OMVAX, INC.Similar federal contract value in Biotech · null in contracts
- HERA TESTING LABORATORIES, INC.Similar federal contract value in Biotech · null in contracts
- Lassogen, Inc.Similar federal contract value in Biotech · null in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .