SEMBA BIOSCIENCES, INC.

MADISON, WI · Founded 2005 · Biotech · Acquired

Continuous simulated moving bed (SMB) chromatography system for monoclonal antibody purification

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Updated Oct 23, 2026

Sector: Biotech
Headquarters: MADISON, WI
Founded: 2005
Latest Form D: $3M, Dec 2018
Total capital: $4.5M

Federal grants: $771K; 1 award · 2015; Rank in peer group#26 of 79
Private capital raised: $3.7M; 4 Form D · last Dec 2018; 95 months since last filing
Federal contracts: None on recordNo federal contract awards found.
Granted patents: 5; 4 pending · first 2015; Rank in peer group#9 of 79

Capital timeline

Latest events

Dec 2018Private capital raisedForm D · SEC · 4th filing$3M
Aug 2015Federal grantHealth and Human S · Phase II · Continuous Chromatography Device to Economically Purify Clinical-grade Antibodies$771K
Jan 2015Private capital raisedForm D · SEC · 3rd filing$511K
Sep 2010Private capital raisedForm D · SEC · 2nd filing$100K
May 2010Private capital raisedForm D · SEC · 1st filing$120K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing among 79 peers

Line = median

Biotech · System

Federal grants#26 · top 33%
Granted patents#9 · top 11%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants

Robert C MierendorfResearcherExecutive OfficerLinked by $771K in grants as PI
Andrew U DeMarcoDirectorNamed in SEC Form D filings
Anil U OroskarPromoterNamed in SEC Form D filings
Asha U OroskarPromoterNamed in SEC Form D filings
Joerg BaierDirectorNamed in SEC Form D filings
John F. HardinDirectorNamed in SEC Form D filings

Show all 12 people

John U. SchellerDirectorNamed in SEC Form D filings
Kenneth U JohnsonDirector, PromoterNamed in SEC Form D filings
Lisa A JohnsonExecutive OfficerNamed in SEC Form D filings
Stanley U GembickiDirectorNamed in SEC Form D filings
Stelios U PapadopoulosDirectorNamed in SEC Form D filings
Steve GordonDirectorNamed in SEC Form D filings

What it has protected

USPTO · 5 granted of 9

Nov 16, 2021GrantedHigh-flow Fluid Valve BlockUSPTOUS 11,174,952
Jul 6, 2021GrantedHigh-flow Fluid Valve BlockUSPTOUS 11,054,045
Oct 22, 2019GrantedHigh-flow Fluid Valve BlockUSPTOUS 10,451,188

Show all 9 patent records

High-flow Fluid Valve BlockNov 16, 2021 · US 11,174,952Granted
High-flow Fluid Valve BlockJul 6, 2021 · US 11,054,045Granted
High-flow Fluid Valve BlockOct 22, 2019 · US 10,451,188Granted
High-flow Fluid Valve BlockAug 27, 2019 · US 10,393,276Granted
Valve Block AssemblyJun 30, 2015 · US 9,068,662Granted
Valve Module And Methods For Simulated Moving Bed ChromatographyApplication PCTUS2007019126Pending
High-flow Fluid Valve BlockApplication PCTUS2015063109Pending
High-flow Fluid Valve BlockApplication PCTUS2014069580Pending
Valve Block AssemblyApplication PCTUS2009051934Pending

TAMUROBIO INC.Similar federal contract value in Biotech · null in contracts
MUSTANG BIO, INC.Similar federal contract value in Biotech · null in contracts
UNDERDOG PHARMACEUTICALS, INC.Similar federal contract value in Biotech · null in contracts
Expansion Technologies, Inc.Similar federal contract value in Biotech · null in contracts
Peel Therapeutics, IncSimilar federal contract value in Biotech · null in contracts
Rgenta Therapeutics, Inc.Similar federal contract value in Biotech · null in contracts

Regulatory activity · Biotech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.