SECOND GENOME, INC.

SAN FRANCISCO, CA · Founded 2009 · Biotech · Private

Platform service analyzing gut microbiome samples to identify metabolites and CNS disease biomarkers for autism and substance use disorder research

Claim this profile

Follows are private to you and power your alerts

Updated

Sector
Biotech
Headquarters
SAN FRANCISCO, CA
Founded
2009
Latest Form D
$5M, Aug 2011
Total capital
$7.9M
Federal grants
$2.1M
3 awards · 2017–2020
Rank in peer group#1 of 37
Private capital raised
$5M
1 Form D · last Aug 2011
183 months since last filing
Federal contracts
$834K
19 awards · Interior, Defense, Environmental Prot
Rank in Biotech#200 of 4373
Granted patents
10
30 pending · first 2018
Rank in peer group#2 of 37

Capital timeline

201020122014201620182020FEDERAL ↑EQUITY ↓Cumulative $7.9M$498K$43K$149K$81K$977K$967K1st Form D$5M
201020122014201620182020FEDERAL ↑EQUITY ↓Cumulative $7.9M$498K$149K$977K$967K1st Form D$5M

Latest events

  • Federal grantHealth and Human S · Phase II · Development of a Commercial Platform for Discovery and Validation of Key Microbial Metabolites in CNS Disorders$967K
  • Federal grantHealth and Human S · Phase II · Development of a Commercial Platform for Discovery and Validation of Key Microbial Metabolites in CNS Disorders$977K
  • Federal contractEnvironmental Prot · Purchase 95 Phylochips And 100 Rxns (4 Tubes) Of Spike Mix For The Region 7 Laboratory$25K
  • Federal contractEnvironmental Prot · Purchase 98 G3 Phylochips And 4 Tubes Of Spike Mix$25K
  • Federal contractHealth and Human S · Igf::ot::igf Microbiome Optimized Dna Isolation Services$81K
  • Federal contractAgriculture · Igf::ct::igf Custom Wetland Analysis Services For Dr. Mark Ibekwe.$4K
  • Federal grantHealth and Human S · Phase II · Development of a Commercial Platform for Discovery and Validation of Key Microbial Metabolites in CNS Disorders$149K
  • Private capital raisedForm D · SEC · 1st filing$5M
Show 15 earlier federal awards
  • Federal contractHealth and Human S · Igf::ot::igf - Second Genome, INC.:1202409 [16-012878]JKRAKOFF$12K
  • Federal contractHealth and Human S · Igf::cl::igf$250
  • Federal contractAgriculture · Microbiome Signature Discovery Service: V4 16S Sequencing And Bioinformatics For Academic Clients (81 Samples), Contaminant Fate&transport Unit, Riverside, Ca Igf::ct::igf$15K
  • Federal contractHealth and Human S · Igf::cl::igf Service$5K
  • Federal contractHealth and Human S · Igf::cl::igf Service$5K
  • Federal contractHealth and Human S · Igf::ot::igf Rrna Sequencing$16K
  • Federal contractAgriculture · Microbiome Discovery Photochip Assay$21K
  • Federal contractHealth and Human S · Igf::ct::igf Service$43K
  • Federal contractCommerce · Sabelfish Nutrition Experiment$28K
  • Federal contractAgriculture · Microbial Profiling Service Quote #00000153$15K
  • Federal contractNASA · Microbial Profiling Service Using Phylochip Technology For Planetary Protection Spacecraft Bioburden Analysis.$10K
  • Federal contractHealth and Human S · Identify The Bacterial Composition In The Gut From Pair-fed&ethanol-fed Mice$10K
  • Federal contractEnvironmental Prot · Phylogenetic Microarray Services$498K
  • Federal contractDefense · Microbial Profiling$11K
  • Federal contractInterior · Grnd Water Sample Analysis-lisle$12K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Federal first

8months

from SECOND GENOME, INC.’s first federal award to its first private round.

First federal award · Dec 2010
Interior · $12K
First Form D · Aug 2011
$5M · 1st Form D
Awards before first raise
3 awards

An association in public records, not a cause or a prediction.

Standing among 37 peers

Line = median

Biotech · Platform

  • Federal grants#1 · top 3%
  • Granted patents#2 · top 5%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

From SEC Form D filings
  • Corey GoodmanDirectorNamed in SEC Form D filings
  • Jason LettmannDirectorNamed in SEC Form D filings
  • Matthew WinklerDirectorNamed in SEC Form D filings
  • Michael CarusiDirectorNamed in SEC Form D filings
  • Peter DiLauraExecutive Officer, DirectorNamed in SEC Form D filings
  • Peter GardnerDirectorNamed in SEC Form D filings

What it has protected

USPTO · 10 granted of 40
Show all 40 patent records
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersJun 6, 2023 · US 11,666,627Granted
  • Methods And Compositions For Treating Type 2 DiabetesFeb 2, 2023 · Application 17758748Pending
  • Methods And Compositions For Treating Atopic DermatitisFeb 2, 2023 · Application 17758773Pending
  • Methods And Compositions For Treating Ulcerative ColitisFeb 2, 2023 · Application 17758713Pending
  • Methods And Compositions For Treating Colorectal CancerFeb 2, 2023 · Application 17758777Pending
  • Proteins for the Treatment of Epithelial Barrier Function DisordersNov 22, 2022 · US 11,505,583Granted
  • Methods For Validation Of Microbiome Sequence Processing And Differential Abundance Analyses Via Multiple Bespoke Spike-in MixturesOct 18, 2022 · US 11,473,133Granted
  • Streptococcus Australis As A BiotherapeuticJul 19, 2022 · US 11,389,487Granted
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersJun 16, 2022 · Application 16614226Pending
  • Gemella Sanguinis As A BiotherapeuticMay 31, 2022 · US 11,344,584Granted
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApr 7, 2022 · Application 17526970Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersMar 15, 2022 · US 11,273,198Granted
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersDec 28, 2021 · US 11,207,376Granted
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersNov 16, 2021 · US 11,174,293Granted
  • Microbial Ecology Shift AssayMay 9, 2019 · Application 16181590Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApr 9, 2019 · US 10,251,933Granted
  • Microbial Ecology Shift AssayDec 11, 2018 · US 10,150,982Granted
  • Microbiome Modulation IndexNov 26, 2015 · Application 14758934Pending
  • Methods And Compositions For Treating Colorectal CancerApplication 62962827Pending
  • Microbially Derived Peptides And Proteins For ImmunotherapyApplication PCTUS2020012431Pending
  • Methods and Compositions for Treating Inflammatory DiseasesApplication 62928232Pending
  • Lactococcus Lactis Expression System For Delivering Proteins Efficacious For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2019055476Pending
  • Compositions, Systems, Apparatuses, And Methods For Validation Of Microbiome Sequence Processing And Differential Abundance Analyses Via Multiple Bespoke Spike-in MixturesApplication PCTUS2019052802Pending
  • Methods for Treating Inflammatory Bowel DiseaseApplication 62834336Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2019026412Pending
  • Microbially Derived Peptides And Proteins For ImmunotherapyApplication 62788950Pending
  • Use Of A P2X7 Receptor Antagonist To Treat An Inflammatory Disease Or DisorderApplication PCTUS2018061037Pending
  • Lactococcus Lactis Expression System For Delivering Proteins Efficacious For The Treatment Of Epithelial Barrier Function DisordersApplication 62743372Pending
  • Compositions, Systems, Apparatuses, And Methods For Validation Of Microbiome Sequence Processing And Differential Abundance Analyses Via Multiple Bespoke Spike-in MixturesApplication 62735374Pending
  • Streptococcus Australis As A BiotherapeuticsApplication PCTUS2018045330Pending
  • Gemella Sanguinis As A BiotherapeuticsApplication PCTUS2018045329Pending
  • Roseburia Hominis, Eubacterium Eligens, And Combinations Thereof As BiotherapeuticsApplication PCTUS2018045239Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2018035682Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2018033347Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2018031046Pending
  • Use Of A P2X7 Receptor Antagonist To Treat An Inflammatory Disease Or DisorderApplication 62655660Pending
  • Proteins For The Treatment Of Epithelial Barrier Function DisordersApplication PCTUS2018026447Pending
  • Proteins for the Treatment of Epithelial Barrier Function DisordersApplication 62654083Pending
  • Stable Proteins For The Treatment Of Gastrointestinal Inflammatory Conditions And Epithelial Barrier Function DisordersApplication 62611334Pending
  • Proteins For The Treatment Of Gastrointestinal Inflammatory Conditions And Epithelial Barrier Function DisordersApplication 62607706Pending

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .