RTM Vital Signs LLC

Philadelphia, PA · Founded 2014 · Medtech · Private

Wearable wireless respiratory monitoring system with acoustic trachea sound sensor and software algorithm for detecting opioid-induced respiratory depression

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Updated Oct 23, 2026 · rtmvitalsigns.com

Sector: Medtech
Headquarters: Philadelphia, PA
Founded: 2014
Latest Form D: $175K, Nov 2017
Total capital: $3.6M

Federal grants: $3.5M; 6 awards · 2019–2026; Rank in peer group#358 of 445
Private capital raised: $175K; 1 Form D · last Nov 2017; 108 months since last filing
Federal contracts: None on recordNo federal contract awards found.
Granted patents: 14; 13 pending · first 2020; Rank in peer group#13 of 445

Capital timeline

Latest events

May 2026Federal grantHealth and Human S · Phase II · Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression$1.3M
Nov 2024Federal grantHealth and Human S · Phase II · Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression$1.3M
Jan 2024Federal grantHealth and Human S · Phase II · Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression$55K
Sep 2023Federal grantHealth and Human S · Phase I · Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression$326K
Sep 2023Federal grantHealth and Human S · Phase II · Wearable Wireless Respiratory Monitoring System that Detects and Predicts Opioid Induced Respiratory Depression$326K
May 2019Federal grantHealth and Human S · Phase I · Development of a tracheal sound sensor for early detection of hypoventilation due to opioid overdose.$236K
Nov 2017Private capital raisedForm D · SEC · 1st filing$175K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing among 445 peers

Line = median

Medtech · Device

Federal grantsBelow median
Granted patents#13 · top 3%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants

Nance DiccianiResearcherExecutive OfficerLinked by 2 patents
Denise L. DevineExecutive OfficerNamed in SEC Form D filings

What it has protected

USPTO · 14 granted of 27

Sep 26, 2023GrantedAlgorithm For Breathing EfficiencyUSPTOUS 11,766,222
Jun 8, 2023PendingImplantable Cardiovasular Monitoring SystemUSPTOApplication 18071858
Jun 8, 2023PendingCardiovascular Monitoring SystemUSPTOApplication 18071860

Show all 27 patent records

Algorithm For Breathing EfficiencySep 26, 2023 · US 11,766,222Granted
Implantable Cardiovasular Monitoring SystemJun 8, 2023 · Application 18071858Pending
Cardiovascular Monitoring SystemJun 8, 2023 · Application 18071860Pending
Acoustic Sensor And Ventilation Monitoring SystemApr 20, 2023 · Application 18082022Pending
Algorithm For Breathing EfficiencyApr 11, 2023 · US 11,622,728Granted
Pressure Sensitive DeviceDec 20, 2022 · US 11,529,100Granted
Acoustic Sensor And Ventilation Monitoring SystemDec 20, 2022 · US 11,529,076Granted
Method Of Determining Respiratory States And Patterns From Tracheal Sound AnalysisMay 26, 2022 · Application 17102545Pending
Implantable Vital Sign SensorMay 17, 2022 · US 11,330,987Granted
Acoustic Sensor And Ventilation Monitoring SystemJan 4, 2022 · US 11,213,225Granted
Acoustic Sensor And Ventilation Monitoring SystemJul 27, 2021 · US 11,071,476Granted
Implantable Vital Sign SensorJul 15, 2021 · Application 17215444Pending
Acoustic Sensor And Ventilation Monitoring SystemMay 18, 2021 · US 11,006,863Granted
Acoustic Sensor And Ventilation Monitoring SystemMay 11, 2021 · US 11,000,212Granted
Acoustic Sensor And Ventilation Monitoring SystemMay 11, 2021 · US 11,000,191Granted
Acoustic Sensor And Ventilation Monitoring SystemJan 5, 2021 · US 10,881,330Granted
Acoustic Sensor And Ventilation Monitoring SystemNov 24, 2020 · US 10,842,416Granted
Punch ToolsNov 17, 2020 · US 10,835,281Granted
Punch ToolsNov 17, 2020 · US 10,835,280Granted
Transvascular Pressure Sensing DeviceDec 5, 2019 · Application 16423515Pending
Algorithm For Breathing EfficiencyApplication 63217487Pending
Implantable Cardiovasular Monitoring SystemApplication 63285149Pending
Optical Methods For Measuring Pressure Long Term To Detect And Monitor Pressure Variations And WaveformsApplication 62256476Pending
Pressure Sensitive DeviceApplication 62679117Pending
Transvascular Pressure Sensing DeviceApplication 62678296Pending
Acoustic Sensor And Ventilation Monitoring SystemApplication 62857963Pending
Acoustic Sensor And Ventilation Monitoring SystemApplication PCTUS2019047009Pending

Prime Genomics, Inc.Similar federal contract value in Medtech · null in contracts
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DURAHIP, LLCSimilar federal contract value in Medtech · null in contracts
TRU DIAGNOSTICS, INC.Similar federal contract value in Medtech · null in contracts
NEUROLIGN USA, LLCSimilar federal contract value in Medtech · null in contracts
ELORAC, INC.Similar federal contract value in Medtech · null in contracts

Regulatory activity · Medtech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.