PRESSURE BIOSCIENCES, INC.

SOUTH EASTON, MA · Biotech · Private

Automated DNA shearing device with active pressure-based nozzle for next-generation sequencing sample preparation

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Updated

Sector
Biotech
Headquarters
SOUTH EASTON, MA
Latest Form D
$17.5M, Mar 2019
Total capital
$31.4M
Federal grants
$1M
1 award · 2014
Rank in peer group#15 of 17
Private capital raised
$28.8M
8 Form D · last Mar 2019
91 months since last filing
Federal contracts
$1.6M
33 awards · Health and Human S, Veterans Affairs, Agriculture
Rank in Biotech#154 of 4373
Granted patents
4
18 pending · first 2016
Rank in peer group#4 of 17

Capital timeline

20042008201220162020FEDERAL ↑EQUITY ↓Cumulative $31.4M$850K$56K$1M$53K$63K$72K1st Form D$1.8M8th Form D$17.5M
20042008201220162020FEDERAL ↑EQUITY ↓Cumulative $31.4M$850K$1M$63K$72K1st Form D$1.8M8th Form D$17.5M

Latest events

  • Federal contractDefense · Barocycler$72K
  • Federal contractHealth and Human S · Pressure Biosciences, INC:1105933 [21-003491]$63K
  • Federal contractHealth and Human S · Constant Systems Multi Shot Cell Disruptor$25K
  • Private capital raisedForm D · SEC · 8th filing$17.5M
  • Federal contractHealth and Human S · Igf::ot::igf For Other Functions$53K
  • Federal contractHealth and Human S · Igf::ot::igf$4K
  • Federal contractHealth and Human S · Igf::ot::igf Barocycler$53K
  • Private capital raisedForm D · SEC · 7th filing$5M
  • Private capital raisedForm D · SEC · 6th filing$1.7M
  • Private capital raisedForm D · SEC · 5th filing$800K
  • Private capital raisedForm D · SEC · 4th filing$826K
  • Private capital raisedForm D · SEC · 3rd filing$20K
  • Private capital raisedForm D · SEC · 2nd filing$1.2M
  • Private capital raisedForm D · SEC · 1st filing$1.8M
Show 27 earlier federal awards
  • Federal contractAgriculture · Igf::ct::igf Barocycler 2320EXT With Delivery, Installation And Training.$43K
  • Federal contractHealth and Human S · Igf::ot::igf - Pressure Biosciences, INC:1105933 [17-009733]$51K
  • Federal contractDefense · Barocycler Pr# 69-4004-17$50K
  • Federal contractHealth and Human S · Igf::it::igf - Specialty Laboratories INC:1105933 [16-010958]$48K
  • Federal contractJustice · Maintenance. (igf::ct::igf)$5K
  • Federal grantHealth and Human S · Phase II · High Pressure Sample Preparation Instrumentation for DNA Sequencing$1M
  • Federal contractCommerce · Cell Disrupter$44K
  • Federal contractHealth and Human S · Igf::ot::igf Barocycler Annual Service Contract$15K
  • Federal contractJustice · One Year Service Pm Contract For A Laboratory Instrument. (igf::ct::igf)$5K
  • Federal contractJustice · One Year Extended Service For Barocycler NEP3229 (igf::ot::igf)$5K
  • Federal contractJustice · Barocycler NEP3229-MSA Pressure Biosciences$5K
  • Federal contractJustice · Barocycler NEP3229$56K
  • Federal contractAgriculture · Shredder, Equipment To Be Used In Extraction Of Dna, Rna And Protien For Evaluation Of Wheat.$4K
  • Federal contractJustice · NEP3229 Re-certification "igf::ot::igf"$6K
  • Federal contractAgriculture · SG3 Kit$3K
  • Federal contractHealth and Human S · Annual Preventive Maintenance Service For A Barocycler$23K
  • Federal contractHealth and Human S · TAS::75 0600::TAS Barocycler And Accessories$31K
  • Federal contractDefense · Osd SBIR Phase I #O093-H19-3159$850K
  • Federal contractAgriculture · Barocycler (3 Month Rental)$3K
  • Federal contractAgriculture · Nep 2320 Barocycler Capable Of 35,000 Psi With Compressor; Shredder Kit And One Year Extended Warranty$18K
  • Federal contractVeterans Affairs · Hcv Rna Genotype Control Panel, 0.6 ML Member$2K
  • Federal contractVeterans Affairs · Series 5000 Positive Control 3 5ML Vials (accurun$1K
  • Federal contractVeterans Affairs · Hcv Rna Linearity Panels, .05ML Per Member$2K
  • Federal contractVeterans Affairs · Hcv Rna Linearity Panels, .05ML Per Member$653
  • Federal contractHealth and Human S · 000HCK72-2006-28115 - Bbi Diagnostics$17K
  • Federal contractHealth and Human S · 000HCK73-2005-17202 - 92DASIR05 - Bbi Diagnostics$19K
  • Federal contractHealth and Human S · 000HCR44-2004-08838 - Bbi Worldwide Panel$3K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

1 record has no date or no amount, so it isn’t placed on the timeline.

Federal first

59months

from PRESSURE BIOSCIENCES, INC.’s first federal award to its first private round.

First federal award · Apr 2004
Health and Human S · $3K
First Form D · Feb 2009
$1.8M · 1st Form D
Awards before first raise
7 awards

An association in public records, not a cause or a prediction.

Standing among 17 peers

Line = median

Biotech · Device

  • Federal grantsBelow median
  • Granted patents#4 · top 24%
  • Linked publications#3 · top 18%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants
  • Edmund Y TingResearcherExecutive OfficerLinked by 3 patents
  • Alexander P LazarevResearcherExecutive OfficerLinked by $1M in grants as PI
  • Alan I. GoldbergDirectorNamed in SEC Form D filings
  • Alan Donald RosensonDirectorNamed in SEC Form D filings
  • Calvin A SaravisDirectorNamed in SEC Form D filings
  • Conrad F. MirExecutive OfficerNamed in SEC Form D filings
Show all 21 people
  • Gregory G. FreitagDirectorNamed in SEC Form D filings
  • Jeffrey N. PetersonDirectorNamed in SEC Form D filings
  • Joseph L. Damasio, Jr.Executive OfficerNamed in SEC Form D filings
  • J Donald PayneDirectorNamed in SEC Form D filings
  • J. Donald PayneDirectorNamed in SEC Form D filings
  • Kevin A. PollackDirectorNamed in SEC Form D filings
  • Matthew B PotterExecutive OfficerNamed in SEC Form D filings
  • Michael S. UrdeaDirectorNamed in SEC Form D filings
  • Nathan P. LawrenceExecutive OfficerNamed in SEC Form D filings
  • P Thomas VogelDirectorNamed in SEC Form D filings
  • R Wayne FritzscheDirectorNamed in SEC Form D filings
  • R. Wayne FritzscheDirectorNamed in SEC Form D filings
  • Richard T SchumacherExecutive Officer, DirectorNamed in SEC Form D filings
  • Richard P. ThomleyExecutive OfficerNamed in SEC Form D filings
  • Vito J. MangiardiDirectorNamed in SEC Form D filings

What it has protected

USPTO · 4 granted of 22
  • PendingHigh Pressure, Wear Resistant Valve For Stop Flow And/or Throttling ControlUSPTOApplication 17764844
  • GrantedUltrahigh Pressure Compact Valve With Throttling CapabilityUSPTOUS 11,156,295
  • PendingMethods And Systems For Protein RefoldingUSPTOApplication 16857633
Show all 22 patent records
  • High Pressure, Wear Resistant Valve For Stop Flow And/or Throttling ControlOct 20, 2022 · Application 17764844Pending
  • Ultrahigh Pressure Compact Valve With Throttling CapabilityOct 26, 2021 · US 11,156,295Granted
  • Methods And Systems For Protein RefoldingNov 12, 2020 · Application 16857633Pending
  • System For High Pressure, High Shear Processing Of FluidsNov 3, 2020 · US 10,823,159Granted
  • Sample Preparation Devices And MethodsJul 14, 2020 · US 10,710,082Granted
  • High Pressure Sample Containment System For Electromagnetic MeasurementsSep 20, 2016 · US 9,448,291Granted
  • Sample Preparation Devices And MethodsApplication PCTUS2015033338Pending
  • Ultrahigh Pressure Homogenizer SystemApplication 62139706Pending
  • Integrated Sample Preparation Devices And MethodsApplication 62005662Pending
  • High Pressure Sample Containment System For Electromagnetic MeasurementsApplication PCTUS2012058792Pending
  • System And Method For Microplate PressurizationApplication PCTUS2011058062Pending
  • Flow-through High Hydrostatic Pressure Microfluidic Sample Preparation Device And Related Methods ThereforApplication PCTUS2011048302Pending
  • Microtube And Related Methods ThereforApplication PCTUS2010033770Pending
  • Shredder For Mechanical Disruption By Gentle Controlled Compressive RotationApplication PCTUS2009057370Pending
  • Extraction Of Biomolecular Complexes Assisted By Alternating Hydrostatic PressureApplication PCTUS2009043168Pending
  • Extraction And Partitioning Of MoleculesApplication PCTUS2008065541Pending
  • Pressure Cycling Systems And Related MethodApplication PCTUS2008052089Pending
  • High Pressure, Wear Resistant Valve For Stop Flow And/or Throttling ControlApplication PCTUS2020053534Pending
  • High Pressure, Wear Resistant Valve Seat Assembly For Stop Flow And/or Throttling ControlApplication 62907983Pending
  • Ultrahigh Pressure C Ompact Valve With Throttling CapabilityApplication PCTUS2016050717Pending
  • System For High Pressure, High Shear Processing Of FluidsApplication PCTUS2016024452Pending
  • Ultrahigh pressure compact valve with throttling capabilityApplication 62217634Pending

Recent research by its founders

  • Green synthesis of building blocks, drug candidates and fine chemicals by barochemistry: application of high pressure in organic synthesis20254 cites
  • High-pressure activation for the solvent- and catalyst-free syntheses of heterocycles, pharmaceuticals and esters20252 cites
  • Theoretical and Experimental Determinations of the Hydrophilic–Lipophilic Balance (HLB) of Representative Oils and Lecithins202427 cites
  • MAKSCIENTIFICSimilar federal contract value in Biotech · $1.6M in contracts
  • INAEDIS, INCSimilar federal contract value in Biotech · $1.6M in contracts
  • ICAGEN, INC.Similar federal contract value in Biotech · $1.6M in contracts
  • SOLARIS VACCINES, INC.Similar federal contract value in Biotech · $1.5M in contracts
  • Arytha Biosciences, LLCSimilar federal contract value in Biotech · $1.5M in contracts
  • FIREBIRD BIOMOLECULAR SCIENCES LLCSimilar federal contract value in Biotech · $1.4M in contracts

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .