Plex Pharmaceuticals, Inc.

San Diego, CA · Biotech · Acquired

Small molecule protease inhibitors targeting flavivirus NS2B-NS3 protease for treatment of dengue, Zika, and West Nile virus infections

plexpharma.com →
Grants
$4.2M
10 awards
Sector median: 1
Raised
—
No Form D on record
Contracts
—
No federal contracts on record
Patents
21
2 granted · 19 pending
Sector median: 2

Capital Timeline

Federal above the line · equity below · node area scaled to amount
Capital and federal award history
DateEventSourceAmount
Federal grantDepartment of Health and Human Services · Phase I · Development of Flavivirus Antivirals Targeting Dengue Virus and WNV Protease$300,000
Federal grantDepartment of Health and Human Services · Phase I · Small molecule activators of alpha-crystallin for non-surgical treatment of cataracts$162,399
Federal grantDepartment of Health and Human Services · Phase I · Small molecule activators of alpha crystallin for non surgical treatment of cataracts$299,173
Federal grantDepartment of Health and Human Services · Phase I · Small molecule activators of alpha-crystallin for non-surgical treatment of cataracts$136,774
Federal grantDepartment of Health and Human Services · Phase I · Discovery and Development of Broad-spectrum Protease Inhibitors of Flaviviruses of Significant Public Health Threats$600,000
Federal grant· 1 of 2 same dayDepartment of Health and Human Services · Phase II · Advancing CAP4196 into in vivo Proof of Concept Translational Studies$1,311,882
Federal grant· 2 of 2 same dayDepartment of Health and Human Services · Phase I · Re-purposing the small-molecule drug, tafamidis (CAP4349) for the non-surgical treatment of cataracts$298,590
Federal grantDepartment of Health and Human Services · Phase I · Discovery and Development of Broad-spectrum Protease Inhibitors of Flaviviruses of Significant Public Health Threats$300,000
Federal grant· 1 of 2 same dayDepartment of Health and Human Services · Phase I · Re-purposing the small-molecule drug, tafamidis (CAP4349) for the non-surgical treatment of cataracts$149,295
Federal grant· 2 of 2 same dayDepartment of Health and Human Services · Phase II · Advancing CAP4196 into in vivo Proof of Concept Translational Studies$648,986
Federal grant · SBIR/STTR

Peer position

Biotech · 4373 companies · ranked on federal contract value
Biotech companies ranked by federal contract value
#CompanyContractsDisclosed equity
1950SCALED MICROBIOMICS, LLC——
1951RYLTI, LLC—$2.3M
1952Cargo Therapeutics—$69M
1953Plex Pharmaceuticals, Inc.——
1954Caring Brands, Inc.—$1.8M
1955KIBIO INC.——
1956SAROS THERAPEUTICS INC——

Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.

Patents

USPTO · 2 granted of 21
  • Dual Acting FKBP12 And FKBP52 Inhibitorsgranted
  • Pharmacological Agents For Treating Ophthalmic Diseasesapplication
  • Pharmacological Agents For Preventing And Treating Cataracts And Presbyopia Eye Diseasesapplication
  • Dual Acting FKBP12 And FKBP52 Inhibitorsgranted
  • Pharmacological Agents For Treating Conditions Of The Eyeapplication
  • Pharmacological Agents For Treating Protein Aggregation Diseases Of The Eyeapplication
  • Pharmacological Agents For Treating Conditions Of The Eyeapplication
  • Pharmacological Agents For Treating Ophthalmic Diseasesapplication
  • Pharmacological Agents For Preventing Treating Cataracts And Presbyopia Eye Diseasesapplication
  • Pharmacological Agents For Treating Myopiaapplication
  • Pharmacological Agents For Treating Protein Aggregation Diseases Of The Eyeapplication
  • Dual Acting FKBP12 And FKBP52 Inhibitorsapplication

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.