PHARMATROPHIX INC

RALEIGH, NC · Founded 2005 · Biotech · Private

Therapeutic drug targeting synaptic resilience in Alzheimer's and neurodegenerative diseases

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Updated · pharmatrophix.com

Sector
Biotech
Headquarters
RALEIGH, NC
Founded
2005
Latest Form D
$5.3M, Jul 2014
Total capital
$6.5M
Federal grants
None on recordNo awards found in SBIR/STTR, NIH, NSF or DoD records.
Private capital raised
$6.5M
4 Form D · last Jul 2014
148 months since last filing
Federal contracts
None on recordNo federal contract awards found.
Granted patents
7
26 pending · first 2016

Capital timeline

20102011201220132014FEDERAL ↑EQUITY ↓Cumulative $6.5M1st Form D$180K2nd Form D$800K4th Form D$5.3M
20102011201220132014FEDERAL ↑EQUITY ↓Cumulative $6.5M2nd Form D$800K

Latest events

  • Private capital raisedForm D · SEC · 4th filing$5.3M
  • Private capital raisedForm D · SEC · 3rd filing$250K
  • Private capital raisedForm D · SEC · 2nd filing$800K
  • Private capital raisedForm D · SEC · 1st filing$180K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing in Biotech · 4373 companies

Line = median
  • Federal contractsBelow median

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

From SEC Form D filings
  • Anne LongoExecutive OfficerNamed in SEC Form D filings
  • Frank LongoDirectorNamed in SEC Form D filings
  • Sallie Shuping-RussellDirectorNamed in SEC Form D filings
  • Robert SimsDirectorNamed in SEC Form D filings

What it has protected

USPTO · 7 granted of 33
  • PendingSalts And Crystalline Forms Of LM11A31 And Methods Of Use ThereofUSPTOApplication 19653997
  • PendingMethods And Compositions For Treating And Managing Alzheimer's DiseaseUSPTOApplication 19393335
  • PendingMethods And Compositions For Treating And Managing Alzheimer's DiseaseUSPTOApplication 18537611
Show all 33 patent records
  • Salts And Crystalline Forms Of LM11A31 And Methods Of Use ThereofSep 10, 2026 · Application 19653997Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseMay 21, 2026 · Application 19393335Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseDec 5, 2024 · Application 18537611Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsMay 26, 2022 · Application 17538821Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsJan 18, 2022 · US 11,225,467Granted
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsJan 14, 2020 · US 10,532,988Granted
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsApr 30, 2019 · US 10,273,219Granted
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsFeb 6, 2018 · US 9,884,833Granted
  • Non-peptide Bdnf Neurotrophin MimeticsNov 28, 2017 · US 9,828,330Granted
  • Non-peptide Bdnf Neurotrophin MimeticsNov 28, 2017 · US 9,828,332Granted
  • Deuterated Compounds Useful For Treating Neurodegenerative DiseasesOct 11, 2016 · US 9,464,066Granted
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsJun 23, 2016 · Application 14972506Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsSep 17, 2015 · Application 14432183Pending
  • Non-peptide Bdnf Neurotrophin MimeticsApplication PCTUS2014028707Pending
  • Non-peptide Bdnf Neurotrophin MimeticsApplication PCTUS2014028201Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsApplication PCTUS2013062025Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsApplication 61785469Pending
  • Polymorph Screen Of LM11A-31 Bis-dihydrogen Sulfate SaltApplication 61706273Pending
  • Deuterated Compounds Useful For Treating Neurodegenerative DiseasesApplication PCTUS2010058345Pending
  • Salts And Crystalline Forms Of LM11A31 And Methods Of Use ThereofApplication PCTUS2025061731Pending
  • Crystalline Forms Of Neurotrophin Mimetic Compounds And Their SaltsApplication PCTUS2010056537Pending
  • Methods And Compositions For Treating And Managing Alzheimer’s DiseaseApplication PCTUS2025052888Pending
  • Salts And Crystalline Forms Of LM11A31 And Methods Of Use ThereofApplication 63740209Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63712958Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication PCTUS2022025127Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63311780Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63306425Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63296678Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63277691Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63275234Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63229948Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63213169Pending
  • Methods And Compositions For Treating And Managing Alzheimer's DiseaseApplication 63212050Pending
  • Axiom Therapeutics Inc.Similar federal contract value in Biotech · null in contracts
  • FluidForm Bio, Inc.Similar federal contract value in Biotech · null in contracts
  • ANTICANCER, INC.Similar federal contract value in Biotech · null in contracts
  • Nanotools BioscienceSimilar federal contract value in Biotech · null in contracts
  • VilyaSimilar federal contract value in Biotech · null in contracts
  • Biotherapeutics, Inc.Similar federal contract value in Biotech · null in contracts

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .