NFlection Therapeutics, Inc.

WAYNE, PA · Founded 2014 · Medtech · Still private

Topical MEK inhibitor gel (NFX) for cutaneous squamous cell carcinoma chemoprevention in organ transplant recipients

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Updated · nflection.com

Sector
Medtech
Headquarters
WAYNE, PA
Founded
2014
Latest Form D
$4M, Jul 2023
Total capital
$15.7M
Federal grants
$300K
1 award
Rank in peer group#5 of 23
Private capital raised
$15.4M
3 Form D · last Jul 2023
39 months since last filing
Federal contracts
None on recordNo federal contract awards found.
Granted patents
7
17 pending · first 2021
Rank in peer group#3 of 23

Capital timeline

2017201820192020202120222023FEDERAL ↑EQUITY ↓Cumulative $15.4M1st Form D$1.4M2nd Form D$10M
2017201920212023FEDERAL ↑EQUITY ↓Cumulative $15.4M1st Form D$1.4M2nd Form D$10M

Latest events

  • Private capital raisedForm D · SEC · 3rd filing$4M
  • Private capital raisedForm D · SEC · 2nd filing$10M
  • Private capital raisedForm D · SEC · 1st filing$1.4M

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

1 record has no date or no amount, so it isn’t placed on the timeline.

Standing among 23 peers

Line = median

Medtech · Molecule

  • Federal grants#5 · top 22%
  • Granted patents#3 · top 13%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants
  • Christopher PowalaResearcherExecutive Officer, DirectorLinked by 1 patent · $300K in grants as PI
  • Corey GoodmanDirectorNamed in SEC Form D filings
  • Josh GrassDirectorNamed in SEC Form D filings
  • Ketan PatelDirectorNamed in SEC Form D filings
  • Mark de SouzaExecutive Officer, DirectorNamed in SEC Form D filings
  • Michael WoottonExecutive Officer, DirectorNamed in SEC Form D filings
Show all 7 people
  • William HodderExecutive Officer, DirectorNamed in SEC Form D filings

What it has protected

USPTO · 7 granted of 24
  • PendingThienyl-aniline Compounds For Treatment Of Dermal DisordersUSPTOApplication 19356850
  • GrantedCrystalline Forms Of A Pyrrolopyridine-aniline CompoundUSPTOUS 12,649,742
  • PendingPyrrolopyridine-aniline Compounds For Treatment Of Dermal DisordersUSPTOApplication 19312825
Show all 24 patent records
  • Thienyl-aniline Compounds For Treatment Of Dermal DisordersJun 18, 2026 · Application 19356850Pending
  • Crystalline Forms Of A Pyrrolopyridine-aniline CompoundJun 9, 2026 · US 12,649,742Granted
  • Pyrrolopyridine-aniline Compounds For Treatment Of Dermal DisordersDec 25, 2025 · Application 19312825Pending
  • Thienyl-aniline Compounds For Treatment Of Dermal DisordersNov 11, 2025 · US 12,466,818Granted
  • Formulations Of Pyrrolopyridine-aniline CompoundsOct 2, 2025 · Application 19187102Pending
  • Naphthyridinone-aniline Compounds For Treatment Of Dermal DisordersAug 5, 2025 · US 12,378,240Granted
  • Formulations Of Pyrrolopyridine-aniline CompoundsMay 27, 2025 · US 12,310,950Granted
  • Processes For Preparing Pyrrolopyridine-aniline CompoundsJul 11, 2024 · Application 18273322Pending
  • Cyanoaryl-aniline Compounds For Treatment Of Dermal DisordersFeb 7, 2023 · US 11,572,344Granted
  • Fused Heteroaromatic-aniline Compounds For Treatment Of Dermal DisordersJan 3, 2023 · US 11,542,271Granted
  • Treatment Of Cognitive Dysfunction With Pyrrolopyridine-aniline CompoundsApr 14, 2022 · Application 17483468Pending
  • Fused Heteroaromatic-aniline Compounds For Treatment Of Dermal DisordersApr 27, 2021 · US 10,988,483Granted
  • Treatment Of Cognitive Dysfunction With Pyrrolopyridine-aniline CompoundsApplication PCTUS2021051710Pending
  • Formulations Of Pyrrolopyridine-aniline CompoundsApplication 63282395Pending
  • Crystalline Forms Of A Pyrrolopyridine-aniline CompoundApplication PCTUS2022013146Pending
  • Processes For Preparing Pyrrolopyridine-aniline CompoundsApplication PCTUS2022013153Pending
  • Crystalline Forms Of A Pyrrolopyridine-aniline CompoundApplication 63139975Pending
  • Processes For Preparing Pyrrolopyridine-aniline CompoundsApplication 63139981Pending
  • Treatment Of Cognitive Dysfunction With Pyrrolopyridine-aniline CompoundsApplication 63082595Pending
  • Thienyl-aniline Compounds For Treatment Of Dermal DisordersApplication PCTUS2019000067Pending
  • Cyanoaryl-aniline Compounds For Treatment Of Dermal DisordersApplication PCTUS2019000068Pending
  • Naphthyridinone-aniline Compounds For Treatment Of Dermal DisordersApplication PCTUS2019000070Pending
  • Topical FormulationsApplication PCTUS2019000066Pending
  • Formulations Of Pyrrolopyridine-aniline CompoundsApplication PCTUS2022050794Pending
  • CICONIA MEDICAL INCSimilar federal contract value in Medtech · null in contracts
  • AMAHEALTH LLCSimilar federal contract value in Medtech · null in contracts
  • MARIZYME, INC.Similar federal contract value in Medtech · null in contracts
  • CALYX, INC.Similar federal contract value in Medtech · null in contracts
  • PROGENTEC DIAGNOSTICS, INC.Similar federal contract value in Medtech · null in contracts
  • Inogen IncSimilar federal contract value in Medtech · null in contracts

Regulatory activity · Medtech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .