NESTED KNOWLEDGE, INC
AI-assisted software platform for automating systematic literature reviews, including search, screening, data extraction, and synthesis with biomedical-specific LLM
- Sector
- Digital health
- Headquarters
- ST. PAUL, MN
- Founded
- 2018
- Latest Form D
- $4.2M, Jan 2026
- Total capital
- $6.6M
- Federal grants
- $501K
- 2 awards · 2020–2024
- Sector median 0 awards
- Private capital raised
- $6.1M
- 6 Form D · last Jan 2026
- 10 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 3
- 4 pending · first 2024
Capital timeline
Latest events
- Private capital raisedForm D · SEC · 6th filing$4.2M
- Federal grantHealth and Human S · Phase I · Automating Tabular Data Extraction to Accelerate Evidence Synthesis and Systematic Literature Review$305K
- Private capital raisedForm D · SEC · 5th filing$1M
- Private capital raisedForm D · SEC · 4th filing$25K
- Private capital raisedForm D · SEC · 3rd filing$800K
- Federal grantHealth and Human S · Phase I · A Comprehensive Data-driven Platform for Acute Ischemic Stroke Patient Outcomes$196K
- Private capital raisedForm D · SEC · 2nd filing$15K
- Private capital raisedForm D · SEC · 1st filing$50K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing in Digital health · 818 companies
Line = median- Federal contractsBelow median
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Karl HolubResearcherExecutive Officer, DirectorLinked by 1 patent
- Kevin KallmesResearcherExecutive Officer, DirectorLinked by $501K in grants as PI
- Dheerendra KommalaDirectorNamed in SEC Form D filings
- Kathryn CowieExecutive OfficerNamed in SEC Form D filings
- Keith KallmesExecutive Officer, DirectorNamed in SEC Form D filings
- Tomas PhilipsonDirectorNamed in SEC Form D filings
What it has protected
USPTO · 3 granted of 7- New patentSystem and Method for Data Gathering and VisualizationUSPTOUS 12,754,947
- New patentSystems And Methods For Performing And Visualizing Semi-automated Systematic Reviews, Ontological Hierarchies, And Network Meta-analysisUSPTOUS 12,755,107
- GrantedSystem and Method for Data Gathering and VisualizationUSPTOUS 12,174,877
Show all 7 patent records
- System and Method for Data Gathering and VisualizationOct 6, 2026 · US 12,754,947Granted
- Systems And Methods For Performing And Visualizing Semi-automated Systematic Reviews, Ontological Hierarchies, And Network Meta-analysisOct 6, 2026 · US 12,755,107Granted
- System and Method for Data Gathering and VisualizationDec 24, 2024 · US 12,174,877Granted
- Systems And Methods For Performing And Visualizing Semi-automated Systematic Reviews, Ontological Hierarchies, And Network Meta-analysisMay 30, 2024 · Application 18523737Pending
- Systems And Methods For Performing And Visualizing Semi-automated Systematic Reviews, Ontological Hierarchies, And Network Meta-analysisApplication 63385607Pending
- Systems And Methods For Performing And Visualizing Semi-automated Systematic Reviews, Ontological Hierarchies, And Network Meta-analysisApplication PCTUS2023081686Pending
- System and Method for Data Gathering and VisualizationApplication 17105972Pending
Related companies, and why
- Alaffia Technology Solutions, Inc.Similar federal contract value in Digital health · null in contracts
- SYNTHESIS ENERGY SYSTEMS INCSimilar federal contract value in Digital health · null in contracts
- Glassbeam, Inc.Similar federal contract value in Digital health · null in contracts
- ProMed IncSimilar federal contract value in Digital health · null in contracts
- 3DR Laboratories LLCSimilar federal contract value in Digital health · null in contracts
- PACIFIC NORTH WEST CAPITAL CORP /CNSimilar federal contract value in Digital health · null in contracts
Regulatory activity · Digital health
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .