MISSION BIO, INC.
Tapestri: a microfluidic droplet platform for high-throughput single-cell DNA sequencing
- Sector
- Medtech
- Headquarters
- SOUTH SAN FRANCISCO, CA
- Latest Form D
- $28.4M, Jul 2018
- Total capital
- $46.9M
- Federal grants
- $5.2M
- 8 awards · 2015–2020
- Rank in peer group#147 of 538
- Private capital raised
- $41.7M
- 2 Form D · last Jul 2018
- 100 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 4
- 36 pending · first 2019
- Rank in peer group#125 of 538
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · Measureable Residual Disease testing for acute myeloid leukemia with single-cell genotyping$992K
- Federal grantHealth and Human S · Phase II · Measureable Residual Disease testing for acute myeloid leukemia with single-cell genotyping$1M
- Private capital raisedForm D · SEC · 2nd filing$28.4M
- Federal grantHealth and Human S · Phase II · A robust platform for high-throughput single-cell genetic variation analysis$951K
- Private capital raisedForm D · SEC · 1st filing$13.3M
- Federal grantHealth and Human S · Phase I · Massively parallel quantitative single-cell PCR with qCell Arrays$200K
- Federal grantNSF · Phase II · SBIR Phase II: Low-cost Detection and Enrichment of Nucleic Acids by Interfacing with Commercially Available Cell Sorters$749K
Show 3 earlier federal awards
- Federal grantHealth and Human S · Phase II · High-throughput single-cell sorting and sequencing with PACS$199K
- Federal grantHealth and Human S · Phase I · Molecular characterization of circulating tumor cells with PCR-activated cell sorting$200K
- Federal grantHealth and Human S · Phase II · High-throughput single-cell sorting and sequencing with PACS$905K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Federal first
26months
from MISSION BIO, INC.’s first federal award to its first private round.
- First federal award · Apr 2015
- Health and Human S · $905K
- First Form D · Jun 2017
- $13.3M · 1st Form D
- Awards before first raise
- 5 awards
An association in public records, not a cause or a prediction.
Standing among 538 peers
Line = medianMedtech · Device
- Federal grants#147 · top 27%
- Granted patents#125 · top 23%
- Linked publications#32 · top 6%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
From SEC Form D filings- Adam Abate, Ph.D.DirectorNamed in SEC Form D filings
- Allison BallmerDirectorNamed in SEC Form D filings
- Brock Siegel, Ph.D.DirectorNamed in SEC Form D filings
- Charles SilverExecutive Officer, DirectorNamed in SEC Form D filings
- Maneesh Jain, Ph.D.DirectorNamed in SEC Form D filings
- Paul Billings, M.D., Ph.D.DirectorNamed in SEC Form D filings
Show all 7 people
- Urshit ParikhDirectorNamed in SEC Form D filings
What it has protected
USPTO · 4 granted of 40- PendingMethod And Apparatus For Simultaneous Targeted Sequencing Of Dna, Rna And ProteinUSPTOApplication 19299158
- PendingPre-enrichment For Single-cell Analysis For Detecting Measurements Of Residual Disease And Analyzing Circulating Tumor CellsUSPTOApplication 18744163
- PendingGene Modification Quantification In Single-cell SequencingUSPTOApplication 18557408
Show all 40 patent records
- Method And Apparatus For Simultaneous Targeted Sequencing Of Dna, Rna And ProteinFeb 5, 2026 · Application 19299158Pending
- Pre-enrichment For Single-cell Analysis For Detecting Measurements Of Residual Disease And Analyzing Circulating Tumor CellsDec 12, 2024 · Application 18744163Pending
- Gene Modification Quantification In Single-cell SequencingJul 4, 2024 · Application 18557408Pending
- Method, System, And Apparatus For Analyzing An Analyte Of A Single CellApr 4, 2024 · Application 18535441Pending
- Methods, Systems And Apparatus For Copy Number Variations And Single Nucleotide Variations Simultaneously Detected In Single-cellsFeb 22, 2024 · Application 17766636Pending
- Method, Systems And Apparatus For Single Cell AnalysisOct 10, 2023 · US 11,781,129Granted
- Single Cell Workflow For Whole Genome AmplificationAug 24, 2023 · Application 17912689Pending
- Method And Apparatus To Normalize Quantitative Readouts In Single-cell ExperimentsJun 6, 2023 · US 11,667,954Granted
- Methods and Systems Involving Digestible Primers for Improving Single Cell Multi-Omic AnalysisMar 30, 2023 · Application 17799495Pending
- Enhanced Detection of Target Nucleic Acids by Removal of DNA-RNA Cross ContaminationMar 30, 2023 · Application 17801017Pending
- Using Machine Learning To Optimize Assays For Single Cell Targeted SequencingMar 16, 2023 · Application 17801097Pending
- Improved Variant Caller Using Single-Cell AnalysisNov 3, 2022 · Application 17766017Pending
- Method And Apparatus For Simultaneous Targeted Sequencing Of Dna, Rna And ProteinOct 20, 2022 · Application 17747783Pending
- Method and Apparatus for Multi-Omic Simultaneous Detection of Protein Expression, Single Nucleotide Variations, and Copy Number Variations in the Same Single CellsOct 13, 2022 · Application 17634841Pending
- Method and Apparatus for Single-Cell Analysis for Determining a Cell TrajectorySep 8, 2022 · Application 17632710Pending
- Method And Apparatus For Simultaneous Targeted Sequencing Of Dna, Rna And ProteinJun 21, 2022 · US 11,365,441Granted
- Method, Apparatus and System to Detect Sub-Particle Flowrate in a Closed SystemMar 3, 2022 · Application 17423194Pending
- Methods, Systems, And Aparatus For Nucleic Acid DetectionSep 9, 2021 · Application 16839057Pending
- Method And Compositions For Evaluating Emulsion UniformityAug 12, 2021 · Application 16639422Pending
- Using Machine Learning to Optimize Assays for Single Cell Targeted DNA SequencingApr 22, 2021 · Application 16936378Pending
- Method, Apparatus and System to Detect Indels and Tandem Duplications Using Single Cell DNA SequencingJan 28, 2021 · Application 16936382Pending
- Methods And Systems For Proteomic Profiling And CharacterizationDec 17, 2020 · Application 16839055Pending
- Method And Systems To Characterize Tumors And Identify Tumor HeterogeneityOct 15, 2020 · Application 16839058Pending
- Methods Of Nucleic Acid Detection And Primer DesignJul 23, 2020 · Application 16749731Pending
- Method, Systems and Apparatus for Single Cell AnalysisDec 10, 2019 · US 10,501,739Granted
- Methods And Compositions For Emulsification Of Solid Supports In Deformable BeadsOct 31, 2019 · Application 16310336Pending
- Method, Systems and Apparatus for High-Throughput Single-Cell DNA Sequencing With Droplet MicrofluidicsApr 18, 2019 · Application 16164595Pending
- Single Cell Viral Integration Site Detection Using TransposonsApplication 63272649Pending
- Cellular Clustering Analysis In Sequencing DatasetsApplication PCTUS2021060186Pending
- Pre-enrichment for Single-Cell Analysis for Detecting Measurements of Residual Disease and Analyzing Circulating Tumor CellsApplication 63290158Pending
- Methods of Molecular Tagging for Single-Cell AnalysisApplication 63301706Pending
- Methods Of Molecular Tagging For Single-cell AnalysisApplication PCTUS2023061040Pending
- Droplet Merger Detection In Single Cell SequencingApplication 63308150Pending
- Method, System, And Apparatus For Analyzing An Analyte Of A Single CellApplication 63317369Pending
- Single-cell Workflow For Detecting Viral Integration Sites And Somatic Genomic VariationsApplication 63407593Pending
- Systems And Methods Of Detecting Merged Droplets In Single Cell SequencingApplication PCTUS2023062313Pending
- Single Cell Analysis For Epigenomic ProfilingApplication PCTUS2022077817Pending
- Method, System, And Apparatus For Analyzing An Analyte Of A Single CellApplication 63327964Pending
- Cellular Clustering Analysis in Sequencing DatasetsApplication 63115713Pending
- De Novo Variant Calling via Multianalyte and Multisample CorrelationApplication 63327966Pending
Recent research by its founders
- Abstract 2440: Single-cell MRD profiling identifies CXCR4-high AML as a responder population to CXCR4 inhibition with Motixafortide20260 cites
- Inhibition of high CXCR4 with Motixafortide and absence of single-cell MRD predict outcome after AML consolidation.20260 cites
- Multiomic Single‐Cell Sequencing Identifies <i>BCR::ABL1</i> as an Acquired Resistance Mechanism in <i>FLT3+</i> <scp>AML</scp>20260 cites
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Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .