ISTO TECHNOLOGIES
OLIVETTE, MO · CIK 0001052380 · Medtech · Acquired
Synthetic biomaterial for cartilage and bone repair in joint lesions
- Grants
- $1.0M
- 2 awards
- Sector median: 1
- Raised
- $21M
- 5 Form D · Jan 2015
- 141 months since last filing
- Contracts
- $1.1M
- 103 awards · Veterans Affairs, Defense
- #303 of 4531 in medtech
- Patents
- 24
- 5 granted · 19 pending
- Sector median: 2
Capital Timeline
Federal ↑Equity ↓20082010201220142016
| Date | Event | Source | Amount |
|---|---|---|---|
| Private capital raised | Form D · SEC | $5,404,890 | |
| Private capital raised | Form D · SEC | $3,272,961 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order | $3,900 | |
| Federal contract | Department of Defense · Bone Graft Extender | $7,960 | |
| Federal contract | Department of Defense · Matrix Strip 5X10 | $30,680 | |
| Federal contract | Department of Defense · Bone Graft Extender | $20,000 | |
| Federal contract | Department of Defense · IQSPMX150 Matrix Strip | $24,885 | |
| Federal contract | Department of Defense · Isto Bone Graft Extender | $5,290 | |
| Federal contract | Department of Defense · Matrix Strip | $30,780 | |
| Federal contract | Department of Defense · Bone Graft Extender Implants | $4,685 | |
| Federal contract | Department of Defense · Paste Mix, Matrix Strip, Putty Plus, Required For Scheduled Surgeries | $68,910 | |
| Federal contract | Department of Defense · IQSPMX150 | $39,040 | |
| Federal contract | Department of Defense · Bone Graft | $4,685 | |
| Federal contract· 1 of 2 same day | Department of Defense · Bonegraftextender | $7,960 | |
| Federal contract· 2 of 2 same day | Department of Defense · Ittimplants | $9,270 | |
| Federal contract | Department of Defense · Bone Graft Extender | $9,975 | |
| Federal contract | Department of Defense · Bone Graft Extender | $14,340 | |
| Federal contract· 1 of 2 same day | Department of Defense · Bonegraftextender | $5,290 | |
| Federal contract· 2 of 2 same day | Department of Defense · Bonegraftex | $4,685 | |
| Federal contract | Department of Defense · Bonegraft | $3,425 | |
| Federal contract | Department of Defense · Inqu Bone Graft Extender | $7,230 | |
| Private capital raised | Form D · SEC | $2,009,365 | |
| Federal contract | Department of Defense · IQSP-99-110 Paste Mix | $17,825 | |
| Federal contract | Department of Veterans Affairs · Bone Graft | $8,145 | |
| Private capital raised | Form D · SEC | $8,000,000 | |
| Federal contract | Department of Veterans Affairs · Bone Graft | $5,915 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order-surg/implt; Po#: W40004; Bx Consult#: 3411247; Doi: 3/28/14; So#: 17906; Model#'s: IQSP-PP&IQSP-MX150; Lot/serial#'s: 113Q026&0530299; Isto Tech | $11,830 | |
| Federal contract· 1 of 2 same day | Department of Veterans Affairs · Surgical Implants | $5,915 | |
| Federal contract· 2 of 2 same day | Department of Veterans Affairs · Surgical Implants | $5,915 | |
| Federal contract | Department of Defense · Bonegraftex | $7,560 | |
| Federal contract | Department of Defense · Bone Graftex | $9,960 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $8,145 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $5,915 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $5,915 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order | $16,290 | |
| Federal contract· 1 of 3 same day | Department of Defense · Bone Graft Extender | $13,380 | |
| Federal contract· 2 of 3 same day | Department of Veterans Affairs · Prosthetics Order - Surgical | $14,060 | |
| Federal contract· 3 of 3 same day | Department of Veterans Affairs · Prosthetics Order - Surgical | $5,915 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $8,145 | |
| Federal contract | Department of Defense · Inqu Matrix - 5X5CM (8.75CC) | $3,545 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $9,095 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $9,095 | |
| Federal contract | Department of Defense · Matrix Strip, Size 5 X 10 IQSPMX150 | $6,180 | |
| Federal contract· 1 of 2 same day | Department of Veterans Affairs · Prosthetics Order - Surgical | $6,865 | |
| Federal contract· 2 of 2 same day | Department of Veterans Affairs · Prosthetics Order - Surgical | $15,010 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $15,010 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $6,865 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $15,010 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $8,200 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $9,095 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $6,865 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Surgical | $15,010 | |
| Private capital raised | Form D · SEC | $2,460,082 | |
| Federal contract | Department of Defense · QSP-PP-110 | $17,840 | |
| Federal contract | Department of Defense · Inqu Matrix 5X10MM P/n IQSP-MX-150B(BONE Graft Extender) | $15,120 | |
| Federal contract | Department of Veterans Affairs · Surg/implt_graft | $11,325 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $15,010 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $6,865 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Bone Graft | $9,095 | |
| Federal contract | Department of Defense · Paste Mix Plus For Medical Surgeries | $24,530 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $9,095 | |
| Federal grant | Department of Health and Human Services · Phase II · Biomaterial augmented microfracture repair of full-thickness chondral defects04 | $224,960 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $10,820 | |
| Federal contract | Department of Defense · Paste Mix Plus 10CC | $4,590 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $5,410 | |
| Federal contract | Department of Veterans Affairs · Curved Rail Stairlift | $5,410 | |
| Federal contract | Department of Defense · Paste Mix Plus 10CC | $6,885 | |
| Federal contract | Department of Defense · Inqu Paste Mix Plus 10CC | $4,590 | |
| Federal contract | Department of Veterans Affairs · Curved Rail Stairlift | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $24,935 | |
| Federal contract | Department of Defense · Inqu Paste Mix Plus 10CC | $9,180 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Bone Graft | $5,410 | |
| Federal contract | Department of Defense · Inqu Paste Mix Plus 10CC | $9,180 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $24,935 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants, Bone Grafts | $20,805 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $12,780 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $16,230 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants (grafts) | $4,515 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $4,515 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $9,095 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $9,060 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Implant Items | $9,095 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $16,220 | |
| Federal contract | Department of Veterans Affairs · Paste Mix Putty Bone Granules | $3,180 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Implant Items | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $14,470 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Items | $6,865 | |
| Federal grant | Department of Health and Human Services · Phase II · Biomaterial augmented microfracture repair of full thickness chondral defects | $810,417 | |
| Federal contract | Department of Defense · Paste Mix Plus, 10CC | $23,860 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Graft | $36,710 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Items | $10,375 | |
| Federal contract | Department of Veterans Affairs · Prosthetics Order - Implant Items | $9,095 | |
| Federal contract | Department of Veterans Affairs · Bone Graft Influx Grains | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $15,010 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant Items | $9,095 | |
| Federal contract | Department of Veterans Affairs · Surgical Implants | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $11,325 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $5,410 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant | $6,060 | |
| Federal contract· 1 of 2 same day | Department of Veterans Affairs · Surgical Implant | $5,410 | |
| Federal contract· 2 of 2 same day | Department of Veterans Affairs · Grafts | $7,290 | |
| Federal contract | Department of Veterans Affairs · Surgical Implant: Posterior Cervical Thoracic Decompression Fusion C6-T2 | $6,515 | |
| Federal contract· 1 of 2 same day | Department of Veterans Affairs · Allograft | $6,685 | |
| Federal contract· 2 of 2 same day | Department of Veterans Affairs · Influx Grains 10CC IFLX-FL-110 Sn CRT150080-209 Bone Graft Extender And Substitute Model #: IQSP-PP-110 Sn 105Q104 Bone Graft Extender And Substitute Model #: IQSP-PP-110 Sn 125Q110 | $5,410 | |
| Federal contract | Department of Veterans Affairs · Graft | $9,095 |
Federal grant · SBIR/STTRFederal contract · USAspendingForm D · SEC
Peer position
| # | Company | Contracts | Disclosed equity |
|---|---|---|---|
| 300 | Microscopy Innovations, LLC | $1.1M | $410K |
| 301 | HEALIONICS CORPORATION | $1.1M | $13M |
| 302 | SINTX TECHNOLOGIES, INC. | $1.1M | — |
| 303 | ISTO TECHNOLOGIES | $1.1M | $21M |
| 304 | HESKA CORP | $1.1M | $132M |
| 305 | Empatica | $1.1M | $27M |
| 306 | TELA Bio, Inc. | $1.1M | $105M |
Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.
Founders & Team
- Christopher Alafi, Ph.D.Director
- Cheryl BlanchardDirector
- Tara ButlerDirector
- George DunbarDirector · Executive Officer
- George Dunbar Jr.Director · Executive Officer
- Joseph FederDirector
- Joseph Feder, Ph.D.Director
- Garry GageExecutive Officer
- Gary GageExecutive Officer
- Scott GillDirector · Executive Officer
- John HartExecutive Officer
- Matthew HermannDirector
- Dean KappelDirector
- Martijn KleljwegtDirector
- William Maloney, M.D.Director
- William Maloney, M.DlDirector
- J. MarchoskyDirector
- James McGorryDirector
- Thomas MelzerDirector
- Blake MilesExecutive Officer
- Mitchell Seyedin, Ph.D.Director · Executive Officer
- James StolzeDirector
- Penny WhiteExecutive Officer
Patents
- Multi-component Injection System And Methods For Tissue Repairgranted
- Neocartilage Compositions And Methods For Modifying Proteoglycan Contentgranted
- Flexible Tissue Matrix And Methods For Joint Repairgranted
- Flexible Tissue Matrix And Methods For Joint Repairgranted
- Delivery Devicegranted
- Intervertebral Disc Repair, Methods And Devices Thereforapplication
- Intervertebral Disc Repair, Methods And Devices Thereforapplication
- Injection Pressure Monitoring Device And Systemapplication
- Cell Expansion Methods And Systemsapplication
- Flexible Tissue Matrixapplication
- Multi-component Injection System And Methods For Tissue Repairapplication
- Flexible Tissue Matrixapplication
Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.