INTEGRATED LABORATORY SYSTEMS, LLC

Biotech · Acquired

Human cell-based mutagenicity assay using duplex sequencing to detect rare mutations for regulatory toxicology

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Updated Oct 23, 2026 · ils-inc.com

Sector: Biotech
Total capital: $276M

Federal grants: $4.4M; 6 awards · 2014–2021; 6.0× sector median 1 award
Private capital raised: None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
Federal contracts: $271M; 130 awards · Health and Human S, Environmental Prot, Defense; Rank in Biotech#2 of 4373
Granted patents: None on recordNo USPTO grants. Applications publish after 18 months.

Capital timeline

Latest events

Jul 2026Federal contractHealth and Human S · Pathology Research For The National Institute Of Environmental Health Sciences - A$3.4M
Jan 2025Federal contractEnvironmental Prot · Acute Oral Tolerability Study-conduct Non-glp Acute Oral Tolerability Study For Each Chemical.$105K
Apr 2024Federal contractEnvironmental Prot · This Doto Is Internal Task Order #6 From The Base Idiq Contract 68HERC22D0010$381K
Jan 2024Federal contractEnvironmental Prot · Mammalian Oral Exposure Studies Internal Task Order 5 Against Integrated Laboratory Systems, Idiq 68HERC22D0010$261K
Sep 2022Federal contractHealth and Human S · Histopathology Services To Support 18 Efficacy Studies With Options For 12 Additional Studies On Viruses With Pandemic Potential$315K
Aug 2022Federal contractEnvironmental Prot · Mammalian Oral Exposure Studies For Ccte. The Purpose Of The Task Order Is For 2 Tolerability Studies And 2- Five Day Repeat Dose Studies For Two Separate Chemicals, As Outlined In Attachment 1 Of This Task Order.$201K
Jun 2022Federal contractEnvironmental Prot · Mammalian Oral Exposure Studies For Ccte$26K

Show 126 earlier federal awards

Sep 2021Federal contractHealth and Human S · Histopathology Services To Support Ongoing SARS-COV-2 Small Animal Efficacy Studies$187K
Apr 2021Federal contractHealth and Human S · Mouse Lung Slides$4K
Feb 2021Federal grantHealth and Human S · Phase I · Mutational profiling in human cells as an in vitro alternative to in vivo mutagenicity assessments$250K
Sep 2020Federal contractHealth and Human S · Genetic Toxicology Support For The Ntp And The Niehs$3.8M
Feb 2020Federal contractHealth and Human S · Pathology$10K
Sep 2018Federal contractHealth and Human S · New Contract Request Entitled" Quantitative Risk Assessment Of Allergenic Fragrance Ingredients Used In Cosmetics Products For The Office Of Cosmetics And Colors$253K
Jul 2017Federal contractHealth and Human S · Igf::ot::igf Pilot Study For In Vivo Genetic Toxicity Of Nnk In Mice Using The Intraperitoneal Route Of Administration$88K
Jun 2017Federal contractHealth and Human S · Igf::ot::igf:: Histopathology Assessment$14K
Apr 2017Federal contractDefense · Igf::ot::igf Methoxyclor (mxc) Rodent Dosing Study$50K
Nov 2016Federal contractDefense · Igf::cl::igf Glp Toxicology Service$66K
Aug 2016Federal contractHealth and Human S · Igf::cl::igf Cosmetic Ingredients Study$214K
Aug 2016Federal grantHealth and Human S · Phase II · Assay Development for Measuring Chemical Effects on the Epigenome in Stem Cells$739K
Jan 2016Federal grantHealth and Human S · Phase II · CometChip: Development of a high throughput DNA damage assay in hepatocytes$701K
Oct 2015Federal contractHealth and Human S · Igf::ot::igf$796K
Sep 2015Federal grantHealth and Human S · Phase II · Assay Development for Measuring Chemical Effects on the Epigenome in Stem Cells$1.5M
Aug 2015Federal contractHealth and Human S · Igf::cl::igf Fragerence Study Titled, "evaluation Of The Allergenicity And Sensitization Potential Of Fragrance Substances Based On Survey Of Scientific Literature."$168K
Jul 2015Federal contractHealth and Human S · Igf::ot::igf Pathology Peer Review And Pathology Support For The Dntp And Dir At Niehs Integrated Logistics Systems (ils); Contract: ; FY15 Funding To Fund The Base Contract Award; Can 8010787$27.5M
May 2015Federal contractHealth and Human S · Igf::cl,ct::igf$41M
Feb 2015Federal grantHealth and Human S · Phase II · CometChip: Development of a high throughput DNA damage assay in hepatocytes$700K
Nov 2014Federal grantHealth and Human S · Phase II · Integration of Genomic Biomarkers with the devTOX Human Embryonic Stem Cells Scre$503K
Aug 2014Federal contractDefense · Igf::ot::igf Rodent Ovarian Follicle Counting And Reporting.$40K
Jul 2014Federal contractHealth and Human S · Igf::ot::igf For Other Functions - Histopathological Analysis$21K
Mar 2014Federal contractHealth and Human S · Igf::ot::igf For Other Functions, Histopathological Services$14K
Nov 2013Federal contractHealth and Human S · Igf::cl,ct::igf Support Contract For National Toxicology Program Interagency Center For The Evaluation Of Alternative Toxicological Methods (niceatm)$4.1M
Sep 2013Federal contractDefense · Definitive Study$354K
Sep 2013Federal contractHealth and Human S · Igf::ot::igf - Genetic Toxicity Testing Services For The Ntp$5.5M
Sep 2013Federal contractEnvironmental Prot · Igf::ot::igf Esat To #33 Cerp (everglades)$35K
Sep 2013Federal contractHealth and Human S · Igf::ot::igf CYP1B1*3 Genotype And Impact On Docetaxel Moa$299K
Mar 2013Federal contractHealth and Human S · Igf::ot::igf For Other Functions - For Pathological Evaluation Of Slides From Mine.$58K
Jan 2013Federal contractDefense · Rat Toxicity Study$418K
Aug 2012Federal contractHealth and Human S · Igf::ot::igf Sample Testing - Other Functions$31K
Apr 2012Federal contractHealth and Human S · Igf::ot::igf (other Function) Pathology Evaluation Of Tissue Samples$19K
Jul 2011Federal contractEnvironmental Prot · $15,000.00 For The ORD/R4 Rare Proposal Support$15K
Jul 2011Federal contractEnvironmental Prot · $10,000 Water Enforcement Support$20K
May 2011Federal contractEnvironmental Prot · Issuance Of Unfunded Task Order.$545K
May 2011Federal contractEnvironmental Prot · Ky. Mountain Top Mining Award Term 3$163K
May 2011Federal contractEnvironmental Prot · Task Order 30$7K
May 2011Federal contractEnvironmental Prot · To 29 Superfund$4.1M
May 2011Federal contractEnvironmental Prot · To 27 Tmdl, Award Term 3$400K
May 2011Federal contractEnvironmental Prot · Issuance Of Unfunded To 0025$145K
May 2011Federal contractEnvironmental Prot · To 28 Rcra$121K
Nov 2010Federal contractHealth and Human S · TAS::75 0862::TAS Report On Carcinogens$7.3M
Jun 2010Federal contractEnvironmental Prot · Gulf Coast Deepwater Horizon Oil Spill$271K
Apr 2010Federal contractEnvironmental Prot · Issue New Task Order (superfund)$2.2M
Apr 2010Federal contractEnvironmental Prot · Issue New Task Order For Rcra$52K
Apr 2010Federal contractEnvironmental Prot · Issue New Task Order$141K
Apr 2010Federal contractEnvironmental Prot · Issue New Task Order PM2.5 Frm$219K
Apr 2010Federal contractEnvironmental Prot · Issue New Task Order NON-PM2.5 Npap$71K
Apr 2010Federal contractEnvironmental Prot · Obligating Funding For New Task Order.$72K
Sep 2009Federal contractEnvironmental Prot · Wpd - Mountain Top Mining, Analytical/field/data Review$46K
Sep 2009Federal contractHealth and Human S · R&d-other R & D-b Res$16.4M
Sep 2008Federal contractHealth and Human S · TAS::75 8062::TAS Support For Preparation Of National Toxicology (ntp) Nomination Background Information And Documents.$2.4M
Apr 2008Federal contractEnvironmental Prot · Technical, Analytical And Qa Support To Epa Superfund Division And Sesd.$3.8M
Apr 2008Federal contractEnvironmental Prot · Technical, Analytical And Quality Assurance Support To Rcra Division And Sesd For Id, Assessment Of Hazards Which May Poste Threat To Human Health Or Environment.$219K
Apr 2008Federal contractEnvironmental Prot · Pm 2.5$408K
Apr 2008Federal contractEnvironmental Prot · NPAP$112K
Apr 2008Federal contractEnvironmental Prot · Technical, Analytical And Quality Assurance Support To Epa Water Mgmt Div And Sesd.$282K
Nov 2007Federal contractEnvironmental Prot$25K
Aug 2007Federal contractEnvironmental Prot · Analysis Of Polymorphisms$67K
Jun 2006Federal contractEnvironmental Prot · To Provide Support To Facilitate Identification, Assessment, Regulation, And Remediation Of Environmental Hazards Which May Pose A Threat To Human Health Or The Environment.$25K
May 2006Federal contractEnvironmental Prot · Comprehensive Everglades Restoration Program Support$33K
Apr 2006Federal contractEnvironmental Prot · Water Management Division Tmdl Analytical/field/data Review/eco-risk Support$518K
Apr 2006Federal contractEnvironmental Prot · Rcra Enforcement Analytical/field/data Review/eco-risk Support$77K
Apr 2006Federal contractEnvironmental Prot · Rcra Program Analytical/field Data/eco-risk Support$106K
Apr 2006Federal contractEnvironmental Prot · Biowatch Program Ambient Air Monitoring Project$507K
Apr 2006Federal contractEnvironmental Prot · Non PM2.5 Performance Evaluation$63K
Apr 2006Federal contractEnvironmental Prot · Superfund Analytical/field/data Review/eco-risk Support$3.1M
Apr 2006Federal contractEnvironmental Prot · Pm 2.5 Frm Performance Evaluation Program Field/laboratory Support$456K
Apr 2006Federal contractEnvironmental Prot · Hurricane Katrina Ambient Air Monitoring Support$52K
Jul 2005Federal contractHealth and Human S · Pathology Support For The Niehs$32.3M
Jul 2005Federal contractHealth and Human S · Pathology Support For Niehs$336K
Apr 2005Federal contractEnvironmental Prot · Esat Superfund Support$878K
Mar 2005Federal contractEnvironmental Prot · Superfund Analytical Support$1.6M
Feb 2005Federal contractEnvironmental Prot · Rcra Enforcement Analytical Support Additional Work$65K
Feb 2005Federal contractEnvironmental Prot · Rcra Support Program$47K
Jan 2005Federal contractEnvironmental Prot · Bio-watch Ambient Monitoring Support$364K
Jan 2005Federal contractEnvironmental Prot · PM2.5 Frm Pep Field Support$126K
Sep 2004Federal contractHealth and Human S · Submarines$5M
Sep 2004Federal contractEnvironmental Prot$141K
Jul 2004Federal contractEnvironmental Prot · The Contractor Shall Perform And Provide Field/laboratory/data Review Support Services To The Epa Region 4 Or Other Government Entities Under The Provisions Of The Contract Statement Of Work (sow) Task Area I, Analytical Support, Task Area II, Data Review Support, Task Area III: Analytical Logistical Support And Task Area Ic, Qa/qc Support.$33K
Apr 2004Federal contractEnvironmental Prot · Superfund Support$968K
Mar 2004Federal contractEnvironmental Prot · Superfund Analytical Support$1.4M
Jan 2004Federal contractEnvironmental Prot · Analytical Support$47K
Jan 2004Federal contractEnvironmental Prot · Analytical Support - Pm 2.5 Frm Performance Evaluation Program$464K
Jan 2004Federal contractEnvironmental Prot · Task Order 15: PM2.5 Frm Pep Field Support Services$147K
Sep 2003Federal contractEnvironmental Prot$1.7M
Sep 2003Federal contractHealth and Human S$1.8M
Sep 2003Federal contractHealth and Human S$28.7M
Sep 2003Federal contractEnvironmental Prot$41K
Sep 2003Federal contractHealth and Human S$17.5M
May 2003Federal contractEnvironmental Prot$24K
May 2003Federal contractEnvironmental Prot$613K
Apr 2003Federal contractHealth and Human S · R&d-other R&d-b Res$25.2M
Mar 2003Federal contractEnvironmental Prot$689K
Feb 2003Federal contractEnvironmental Prot$1.4M
Feb 2003Federal contractEnvironmental Prot$526K
Feb 2003Federal contractEnvironmental Prot$222K
Dec 2002Federal contractEnvironmental Prot$140K
Dec 2002Federal contractEnvironmental Prot$256K
Aug 2002Federal contractEnvironmental Prot$197K
Jun 2002Federal contractHealth and Human S$740K
May 2002Federal contractEnvironmental Prot$171K
Apr 2002Federal contractEnvironmental Prot$17K
Apr 2002Federal contractEnvironmental Prot$268K
Mar 2002Federal contractEnvironmental Prot$1.1M
Mar 2002Federal contractEnvironmental Prot$877K
Feb 2002Federal contractEnvironmental Prot$1.4M
Jan 2002Federal contractEnvironmental Prot$238K
Jan 2002Federal contractEnvironmental Prot$123K
Dec 2001Federal contractEnvironmental Prot$23K
Jun 2001Federal contractEnvironmental Prot · City Of Mcfarland Superfund Site$3K
Jun 2001Federal contractEnvironmental Prot$579K
May 2001Federal contractEnvironmental Prot$129K
May 2001Federal contractEnvironmental Prot$313K
May 2001Federal contractEnvironmental Prot$773K
Mar 2001Federal contractEnvironmental Prot$121K
Feb 2001Federal contractEnvironmental Prot$343K
Feb 2001Federal contractEnvironmental Prot$283K
Feb 2001Federal contractEnvironmental Prot$15K
Feb 2001Federal contractEnvironmental Prot$26K
Feb 2001Federal contractEnvironmental Prot$192K
Feb 2001Federal contractEnvironmental Prot$15K
Feb 2001Federal contractEnvironmental Prot$277K
Feb 2001Federal contractEnvironmental Prot$115K
Oct 1999Federal contractHealth and Human S$1.1M
Apr 1998Federal contractHealth and Human S · R&d-other R&d-b Res$4.7M

Federal awards are summed by year (133 awards); hover a bar for the split. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

3 records have no date or no amount, so they aren’t placed on the timeline.

Standing in Biotech · 4373 companies

Line = median

Federal contracts#2 · top 1%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

No founders are linked to this company yet.

Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.

Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026

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What it has protected

No granted patents are on record.

USPTO usually publishes applications 18 months after filing, so recent applications may not be visible yet. Patents assigned under a different entity name won’t match.

Checked: USPTO granted patents and published applications · Oct 23, 2026

MAPP BIOPHARMACEUTICAL, INC.Similar federal contract value in Biotech · $586M in contracts
VENATORX PHARMACEUTICALS INCSimilar federal contract value in Biotech · $270M in contracts
AchaogenSimilar federal contract value in Biotech · $214M in contracts
Ginkgo BioworksSimilar federal contract value in Biotech · $191M in contracts

Regulatory activity · Biotech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.