FLUENT BIOSCIENCES INC
PIPseq, a scalable single-cell RNA sequencing method using pretemplated instant partitioning that eliminates need for custom microfluidics
- Sector
- Biotech
- Headquarters
- Watertown, MA
- Total capital
- $11.3M
- Federal grants
- $11.2M
- 13 awards · 2019–2023
- Rank in peer group#10 of 42
- Private capital raised
- None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
- Federal contracts
- $96K
- 6 awards · Health and Human S
- Rank in Biotech#334 of 4373
- Granted patents
- 6
- 34 pending · first 2021
- Rank in peer group#6 of 42
Capital timeline
Latest events
- Federal contractHealth and Human S · Consumable Biological Reagent Products$15K
- Federal contractHealth and Human S · Proprietary Biological/reagent Products$11K
- Federal contractHealth and Human S · Fluent Biosciences Reagents Including Pipseq Rna Kits, Fluent V Nuclei Isolation Kits, And Pipseq V Universal Upgrade Starter Kits (ambis #2229743)$30K
- Federal contractHealth and Human S · Fluent Rna Kits (ambis #2231813)$11K
- Federal contractHealth and Human S · Proprietary Biological/reagent Products$15K
- Federal grantHealth and Human S · Phase II · Commercialization of methods and reagents for high-throughput single cell analysis$1.1M
- Federal grantHealth and Human S · Phase II · Commercialization of methods and reagents for high-throughput single cell analysis$1.1M
Show 12 earlier federal awards
- Federal contractHealth and Human S · Fluent Biosciences (ambis #2185053)$14K
- Federal grantHealth and Human S · Phase II · New tools for highly accessible single cell RNA sequencing$775K
- Federal grantHealth and Human S · Phase II · New tools for highly accessible single cell RNA sequencing$1.7M
- Federal grantHealth and Human S · Phase II · New tools for highly accessible single cell RNA sequencing$904K
- Federal grantHealth and Human S · Phase II · Custom assays for personalized, longitudinal monitoring of circulating tumor DNA using PIPSenSeq$826K
- Federal grantHealth and Human S · Phase II · Custom assays for personalized, longitudinal monitoring of circulating tumor DNA using PIPSenSeq$1.9M
- Federal grantHealth and Human S · Phase II · Custom assays for personalized, longitudinal monitoring of circulating tumor DNA using PIPSenSeq$1.1M
- Federal grantHealth and Human S · Phase I · PIPsceq: powering single cell RNA sequencing into the million cell era$399K
- Federal grantHealth and Human S · Phase I · PIPsceq: powering single cell RNA sequencing into the million cell era$399K
- Federal grantHealth and Human S · Phase I · Anti-cancer drug screening enabled by Pre-templated Instant Partitions and single cell RNA sequencing$288K
- Federal grantHealth and Human S · Phase I · Anti-cancer drug screening enabled by Pre-templated Instant Partitions and single cell RNA sequencing$288K
- Federal grantHealth and Human S · Phase II · Custom assays for personalized, longitudinal monitoring of circulating tumor DNA using PIPSenSeq$299K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 42 peers
Line = medianBiotech · Instrument
- Federal grants#10 · top 24%
- Granted patents#6 · top 14%
- Linked publications#10 · top 24%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
No founders are linked to this company yet.
Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.
Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026
Claim this profile to add your teamWhat it has protected
USPTO · 6 granted of 40- GrantedQuantitative Detection And Analysis Of MoleculesUSPTOUS 11,976,325
- GrantedMulti-omic Analysis In Monodisperse DropletsUSPTOUS 11,866,782
- GrantedMethods And Systems For Single Cell Gene ProfilingUSPTOUS 11,827,936
Show all 40 patent records
- Quantitative Detection And Analysis Of MoleculesMay 7, 2024 · US 11,976,325Granted
- Multi-omic Analysis In Monodisperse DropletsJan 9, 2024 · US 11,866,782Granted
- Methods And Systems For Single Cell Gene ProfilingNov 28, 2023 · US 11,827,936Granted
- Single Cell SequencingOct 3, 2023 · US 11,773,452Granted
- Emulsion Based Drug ScreeningNov 29, 2022 · US 11,512,337Granted
- Single Cell SequencingAug 31, 2021 · US 11,104,961Granted
- Decentralized Workflows For Single Cell AnalysisApplication PCTUS2022037129Pending
- Devices For Generating Pre-templated Instant PartitionsApplication PCTUS2022036464Pending
- Methods And Compositions For Nucleic Acid AnalysisApplication PCTUS2022035468Pending
- Scrnaseq Analysis SystemsApplication 63354910Pending
- Spatial Transcriptomics In PipsApplication PCTUS2022031061Pending
- Pre-templated Instant Partitions For ScreeningApplication PCTUS2022029637Pending
- Template Particles With Micropores And NanoporesApplication PCTUS2022029636Pending
- Perturbed Genomic Expression In Pretemplated Instant PartitionsApplication PCTUS2022029692Pending
- Multi-omic Analysis Of Extracellular Vesicles In Monodisperse DropletsApplication PCTUS2022029635Pending
- Methods For Performing Digital PcrApplication PCTUS2022029641Pending
- Emulsification With Magnetic HydrogelsApplication PCTUS2022013720Pending
- Devices For Improving Sample Preparation And ProcessingApplication 63275152Pending
- Methods And Systems For Detecting Pathogenic Microbes In A PatientApplication PCTUS2021057868Pending
- Systems And Methods For Making Sequencing LibrariesApplication PCTUS2021057857Pending
- Pre-templated Instant Partitioning Of Dna-encoded LibrariesApplication 63222135Pending
- Decentralized Workflows For Single Cell AnalysisApplication 63222213Pending
- Tiered Ligation OligosApplication PCTUS2021041810Pending
- Devices For Generating Pre-templated Instant PartitionsApplication 63220097Pending
- Methods And Compositions For Nucleic Acid AnalysisApplication 63216961Pending
- Spatial Transcriptomics In PipsApplication 63194356Pending
- Pre-templated Instant Partitions For ScreeningApplication 63190058Pending
- Methods For Performing Digital PcrApplication 63190150Pending
- Perturbed Genomic Expression In Pretemplated Instant PartitionsApplication 63190125Pending
- Multi-omic Analysis Of Extracellular Vesicles In Monodisperse DropletsApplication 63190079Pending
- Template Particles With Micropores And NanoporesApplication 63190148Pending
- Viral Detection Using Template EmulsificationApplication PCTUS2021023815Pending
- Multi-omic Analysis In Monodisperse DropletsApplication PCTUS2021022503Pending
- Emulsification With Magnetic HydrogelsApplication 63141064Pending
- Methods And Systems For Single Cell Gene ProfilingApplication PCTUS2021013042Pending
- Methods And Systems For Amplifying Low Concentrations Of Nucleic AcidsApplication PCTUS2021013045Pending
- Single Cell SequencingApplication PCTUS2021013066Pending
- Reverse Transcription During Template EmulsificationApplication PCTUS2021013065Pending
- Devices For Generating Monodisperse Droplets From A Bulk LiquidApplication PCTUS2021013048Pending
- Emulsion Based Drug ScreeningApplication PCTUS2021013069Pending
Recent research by its founders
- Multiomic single cell sequencing identifies stemlike nature of mixed phenotype acute leukemia202417 cites
- Intrinsic molecular identifiers enable robust molecular counting in single-cell sequencing20245 cites
- Microfluidics-free single-cell genomics with templated emulsification2023217 cites
Related companies, and why
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- Data2Discovery IncSimilar federal contract value in Biotech · $97K in contracts
- Bellbrook Labs, LLCSimilar federal contract value in Biotech · $90K in contracts
- FINA BIOSOLUTIONS LLCSimilar federal contract value in Biotech · $83K in contracts
- Celularity IncSimilar federal contract value in Biotech · $80K in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .