Enzyme by Design Inc.

Biotech · Private

EBD-300, a next-generation mammalian L-asparaginase enzyme therapeutic with reduced immunogenicity and zero off-target glutaminase activity, engineered for longer in vivo persistence to treat acute ly

enzymebydesign.com →
Grants
$4.2M
11 awards
Sector median: 1
Raised
—
No Form D on record
Contracts
—
No federal contracts on record
Patents
—
No published records under this name
Sector median: 2

Capital Timeline

Federal above the line · equity below · node area scaled to amount
Capital and federal award history
DateEventSourceAmount
Federal grantDepartment of Health and Human Services · Phase I · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$298,305
Federal grantDepartment of Health and Human Services · Phase I · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$353,305
Federal grantDepartment of Health and Human Services · Phase I · Development of a novel safe and efficacious biologic drug for the treatment of AML$299,552
Federal grantDepartment of Health and Human Services · Phase I · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$55,000
Federal grantDepartment of Health and Human Services · Phase I · Maximizing the safety profile of a novel cancer therapeutic via the de-immunization of an engineered mammalian asparaginase$299,939
Federal grantDepartment of Health and Human Services · Phase I · Maximizing the safety profile of a novel cancer therapeutic via the de-immunization of an engineered mammalian asparaginase$149,999
Federal grantDepartment of Health and Human Services · Phase I · Extending the in vivo half-life of a novel engineered mammalian asparaginase via its binding to human serum albumin$399,999
Federal grantDepartment of Health and Human Services · Phase II · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$1,156,734
Federal grantDepartment of Health and Human Services · Phase II · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$1
Federal grantDepartment of Health and Human Services · Phase II · A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy$836,804
Federal grantDepartment of Health and Human Services · Phase I · Engineering in vivo half-life extension of a novel mammalian asparaginase to increase feasibility of pan-cancer therapy$400,000
Federal grant · SBIR/STTR

Peer position

Biotech · 4373 companies · ranked on federal contract value
Biotech companies ranked by federal contract value
#CompanyContractsDisclosed equity
1495GFREE BIO, LLC——
1496BEXION PHARMACEUTICALS, INC.——
1497Viewpoint Therapeutics, Inc.—$25M
1498Enzyme by Design Inc.——
1499Calporta Therapeutics——
1500Atavistik Bio——
1501Ring Therapeutics——

Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.