DOTY SCIENTIFIC, INC.

Columbia, SC · Medtech · Private

Ultra-low-temperature (6 K) static NMR-DNP probe for solid-state nuclear magnetic resonance analysis of proteins and materials

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Updated Oct 23, 2026 · dotynmr.com

Sector: Medtech
Headquarters: Columbia, SC
Total capital: $22.4M

Federal grants: $22.4M; 29 awards · 2015–2026; Rank in peer group#3 of 112
Private capital raised: None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
Federal contracts: None on recordNo federal contract awards found.
Granted patents: 5; 8 pending · first 2015; Rank in peer group#10 of 112

Capital timeline

Latest events

May 2026Federal grantHealth and Human S · Phase II · Ultra-low-temperature (6 K) static NMR-DNP for metalloproteins, proteins in cells, and materials$946K
Jul 2025Federal grantHealth and Human S · Phase I · An HR-MAS H/F/X/Y UHF NMR Probe for Allosteric Drug Research at Physiological Conditions$300K
Jan 2025Federal grantHealth and Human S · Phase II · A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets$791K
Dec 2024Federal grantHealth and Human S · Phase II · Ultra-low-temperature (6 K) static NMR-DNP for metalloproteins, proteins in cells, and materials$983K
Sep 2024Federal grantHealth and Human S · Phase I · Low-loss Bi-directional THz Couplers to Enable Affordable MAS-DNP-NMR$307K
Jan 2024Federal grantHealth and Human S · Phase II · A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets$848K
Jul 2023Federal grantHealth and Human S · Phase II · A Reliable Switched Angle Spinning (SAS) Probe with Gradients (PFG) for Proteins in Solid-State NMR$641K

Show 22 earlier federal awards

Mar 2023Federal grantHealth and Human S · Phase I · Ultra-low-temperature (6 K) static NMR-DNP for metalloproteins, proteins in cells, and materials$300K
Jan 2023Federal grantHealth and Human S · Phase II · A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets$861K
Jul 2022Federal grantHealth and Human S · Phase II · A Reliable Switched Angle Spinning (SAS) Probe with Gradients (PFG) for Proteins in Solid-State NMR$668K
Aug 2021Federal grantHealth and Human S · Phase II · An H/F/X/Y Fast-MAS NMR Probe Particularly for Alzheimer's and Cancer Research$983K
Aug 2021Federal grantHealth and Human S · Phase II · A Reliable Switched Angle Spinning (SAS) Probe with Gradients (PFG) for Proteins in Solid-State NMR$2M
Feb 2021Federal grantHealth and Human S · Phase I · High-order Cavities for Enabling High-field MAS-DNP-NMR with Low-cost THz Sources$300K
Aug 2020Federal grantHealth and Human S · Phase I · A Novel Waveguide to Enable MAS-DNP-NMR in Standard-bore High-field Magnets$297K
Aug 2020Federal grantHealth and Human S · Phase II · An H/F/X/Y Fast-MAS NMR Probe Particularly for Alzheimer's and Cancer Research$2M
Aug 2019Federal grantHealth and Human S · Phase II · An HXYZ-g HR-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations$643K
Jul 2019Federal grantHealth and Human S · Phase II · An HXYZ-g HR-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations$680K
Mar 2019Federal grantHealth and Human S · Phase I · An Efficient System for 30-K MAS-NMR-DNP for Macromolecule Structure Determinations$225K
Sep 2018Federal grantHealth and Human S · Phase I · A Reliable Switched Angle Spinning (SAS) Probe with Gradients (PFG) for Proteins in Solid-State NMR$224K
Jul 2018Federal grantHealth and Human S · Phase II · An HXYZ-g HR-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations$694K
Sep 2017Federal grantHealth and Human S · Phase I · A Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes$225K
Sep 2017Federal grantHealth and Human S · Phase I · A Novel Millimeter-wave (mmw) DNP/EPR Front-end Compatible with Versatile High-field NMR Probes$225K
Aug 2017Federal grantHealth and Human S · Phase II · Closed-Loop MAS-DNP-NMR at 30 K for Affordable Dramatic Gains in S/N$700K
Aug 2017Federal grantHealth and Human S · Phase II · An HXYZ-g HR-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations$2.7M
Aug 2016Federal grantHealth and Human S · Phase II · Closed-Loop MAS-DNP-NMR at 30 K for Affordable Dramatic Gains in S/N$687K
Apr 2016Federal grantHealth and Human S · Phase I · An H/F/X/Y Fast-MAS NMR Probe Particularly for Alzheimer’s and Cancer Research$224K
Mar 2016Federal grantHealth and Human S · Phase I · A Quad-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations$224K
Sep 2015Federal grantHealth and Human S · Phase II · Closed Loop MAS DNP NMR at K for Affordable Dramatic Gains in S N$2.1M
Sep 2015Federal grantHealth and Human S · Phase II · Closed-Loop MAS-DNP-NMR at 30 K for Affordable Dramatic Gains in S/N$686K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing among 112 peers

Line = median

Medtech · Instrument

Federal grants#3 · top 3%
Granted patents#10 · top 9%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

No founders are linked to this company yet.

Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.

Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026

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What it has protected

USPTO · 5 granted of 13

Jul 7, 2026GrantedSea multicopterUSPTOUS 12,673,754
Apr 23, 2026PendingBidirectional overmoded THz couplerUSPTOApplication 19120849
Jun 17, 2025GrantedNMR probe for efficient MAS-DNP operation at ultra-low temperaturesUSPTOUS 12,332,329

Show all 13 patent records

Sea multicopterJul 7, 2026 · US 12,673,754Granted
Bidirectional overmoded THz couplerApr 23, 2026 · Application 19120849Pending
NMR probe for efficient MAS-DNP operation at ultra-low temperaturesJun 17, 2025 · US 12,332,329Granted
Terahertz waveguide comprising an outer copper layer laminated with an inner dielectric layer to form a rolled guide tube which is encased by a support tubeMay 7, 2024 · US 11,978,943Granted
Tunable microwave resonator for static dynamic nuclear polarization (DNP)Sep 18, 2018 · US 10,078,120Granted
Stabilizing control of a saturated cold gas streamJun 23, 2015 · US 9,062,904Granted
Hydrocarbon and alcohol fuels from variable, renewable energy at very high efficiencyFeb 7, 2013 · Application 13650578Pending
Compact, High-effectiveness, Gas-to-gas Compound Recuperator With Liquid IntermediaryApplication PCTUS2008067008Pending
Hydrocarbon And Alcohol Fuels From Variable, Renewable Energy At Very High EfficiencyApplication PCTUS2008057386Pending
High-temperature Dual-source Organic Rankine Cycle With Gas SeparationsApplication PCTUS2007085484Pending
Rolled-laminate Terahertz WaveguideApplication 63268362Pending
Improved Nmr Cryomas Probe For High-field Wide-bore MagnetsApplication PCTUS2007085040Pending
NMR Probe for Efficient MAS-DNP Operation at Ultra-low TemperaturesApplication 63580298Pending

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Regulatory activity · Medtech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.