CLAIRIgene
Durham, NC · Biotech · Private
Epigenome editing tools using dCas9-epigenome modifier fusion proteins delivered via lentiviral vectors to selectively downregulate APOE e4 allele expression for Alzheimer's disease
clairigene.com →- Grants
- $1.3M
- 3 awards
- Sector median: 1
- Raised
- —
- No Form D on record
- Contracts
- —
- No federal contracts on record
- Patents
- —
- No published records under this name
- Sector median: 2
Capital Timeline
Federal ↑Equity ↓20222023
| Date | Event | Source | Amount |
|---|---|---|---|
| Federal grant | Department of Health and Human Services · Phase I · APOE-targeted therapy for precision medicine in late onset Alzheimer's disease: A novel epigenome editing approach for downregulation of APOEe4 expression | $492,903 | |
| Federal grant | Department of Health and Human Services · Phase I · APOE-targeted therapy for precision medicine in late onset Alzheimer's disease: A novel epigenome editing approach for downregulation of APOEe4 expression | $492,903 | |
| Federal grant | Department of Health and Human Services · Phase I · A novel producer cell line for more efficient manufacturing of viral vector systems | $330,532 |
Federal grant · SBIR/STTR
Peer position
| # | Company | Contracts | Disclosed equity |
|---|---|---|---|
| 1996 | Ionetix Corp / DE / | — | $32M |
| 1997 | JYANT, INC. | — | — |
| 1998 | CERAMIDE THERAPEUTICS, LLC | — | — |
| 1999 | CLAIRIgene | — | — |
| 2000 | Compass Therapeutics | — | $256M |
| 2001 | NiKang Therapeutics | — | $200M |
| 2002 | Regulonix | — | — |
Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.