Celldex Therapeutics
Humanized monoclonal antibody (barzolvolimab) targeting KIT receptor tyrosine kinase to modulate mast cell function in inflammatory and autoimmune diseases
- Sector
- Biotech
- Headquarters
- HAMPTON, NJ
- Latest Form D
- $62.5M, Nov 2016
- Total capital
- $68.1M
- Federal grants
- $5.4M
- 5 awards · 2015–2021
- 5.0× sector median 1 award
- Private capital raised
- $62.5M
- 1 Form D · last Nov 2016
- 119 months since last filing
- Federal contracts
- $199K
- 1 award · Health and Human S
- Rank in Biotech#295 of 4373
- Granted patents
- 19
- 21 pending · first 2019
- Rank in peer group#81 of 1449
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · Immune modulation of radiation therapy with Flt3 ligand$1.6M
- Federal grantHealth and Human S · Phase II · Immune modulation of radiation therapy with Flt3 ligand$1.2M
- Private capital raisedForm D · SEC · 1st filing$62.5M
- Federal grantHealth and Human S · Phase II · Immune modulation of radiation therapy with Flt3 ligand$539K
- Federal grantHealth and Human S · Phase II · Immune modulation of radiation therapy with Flt3 ligand$1.1M
- Federal grantHealth and Human S · Phase II · Dendritic Cell-Targeted HIV Vaccine Product$988K
- Federal contractHealth and Human S · Igf::ot::igf Other Functions - R&d Biomedical (basic Research)$199K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Federal first
50months
from Celldex Therapeutics’s first federal award to its first private round.
- First federal award · Sep 2012
- Health and Human S · $199K
- First Form D · Nov 2016
- $62.5M · 1st Form D
- Awards before first raise
- 4 awards
An association in public records, not a cause or a prediction.
Standing among 1449 peers
Line = medianBiotech · Molecule
- Granted patents#81 · top 6%
- Linked publications#1 · top 1%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
From SEC Form D filings- Anthony S. MarucciExecutive Officer, DirectorNamed in SEC Form D filings
- Avery W. CatlinExecutive OfficerNamed in SEC Form D filings
- George O. ElstonDirectorNamed in SEC Form D filings
- Harry H. Penner, Jr.DirectorNamed in SEC Form D filings
- Herbert J. ConradDirectorNamed in SEC Form D filings
- Karen O. ShoosDirectorNamed in SEC Form D filings
Show all 9 people
- Larry J. EllbergerDirectorNamed in SEC Form D filings
- Richard H. van den BroekDirectorNamed in SEC Form D filings
- Timothy M. Shannon, M. D.DirectorNamed in SEC Form D filings
What it has protected
USPTO · 19 granted of 40- PendingAgonistic Antibodies That Bind Human CD40 And Uses ThereofUSPTOApplication 19183513
- PendingAnti-kit Antibody Formulations And MethodsUSPTOApplication 18998418
- PendingANTI-PD-L1 Antibodies And Methods Of Use ThereofUSPTOApplication 18962161
Show all 40 patent records
- Agonistic Antibodies That Bind Human CD40 And Uses ThereofApr 30, 2026 · Application 19183513Pending
- Anti-kit Antibody Formulations And MethodsFeb 26, 2026 · Application 18998418Pending
- ANTI-PD-L1 Antibodies And Methods Of Use ThereofNov 13, 2025 · Application 18962161Pending
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentMay 15, 2025 · Application 19025631Pending
- Agonistic Antibodies That Bind Human CD40 And Uses ThereofMay 13, 2025 · US 12,297,266Granted
- Agonistic Antibodies That Bind CD40Apr 10, 2025 · Application 18749869Pending
- CD27 AgonistsFeb 20, 2025 · Application 18667334Pending
- Antibodies Against ILT4, Bispecific ANTI-ILT4/PD-L1 Antibody And Uses ThereofDec 19, 2024 · Application 18283742Pending
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentOct 31, 2024 · Application 18628224Pending
- Treatment Of Eosinophil Or Mast Cell Related DisordersAug 29, 2024 · Application 18634562Pending
- Treatment Of Eosinophil Or Mast Cell Related DisordersMay 21, 2024 · US 11,987,626Granted
- Anti-kit Antibodies And Uses ThereofMay 9, 2024 · Application 18543874Pending
- Anti-kit Antibodies And Uses ThereofMay 2, 2024 · Application 18538698Pending
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentApr 23, 2024 · US 11,965,031Granted
- Anti-kit Antibodies And Uses ThereofApr 11, 2024 · Application 18273680Pending
- Treatment Of Chronic PrurigoApr 4, 2024 · Application 18273683Pending
- Anti-kit Antibodies And Uses ThereofFeb 6, 2024 · US 11,891,452Granted
- Anti-kit Antibodies And Uses ThereofJan 30, 2024 · US 11,884,699Granted
- Anti-MET Antibodies and Methods of Use ThereofJan 30, 2024 · US 11,884,734Granted
- Chimeric Antigen Receptors Targeting TIM-1Jan 3, 2023 · US 11,541,076Granted
- ANTI-CD27 And ANTI-PD-L1 Antibodies And Bispecific ConstructsOct 13, 2022 · Application 17720954Pending
- ANTI-CD27 And ANTI-PD-L1 Antibodies And Bispecific ConstructsOct 4, 2022 · US 11,459,393Granted
- Antibodies That Bind Human CD27 And Uses ThereofJul 21, 2022 · Application 17507895Pending
- Anti-axl Antibodies And Methods Of Use ThereofJun 9, 2022 · Application 17598005Pending
- ANTI-CD27 And ANTI-PD-L1 Antibodies And Bispecific ConstructsMay 17, 2022 · US 11,332,537Granted
- Methods Of Using CD27 Antibodies As Conditioning Treatment For Adoptive Cell TherapyJan 20, 2022 · Application 17298071Pending
- Antibodies That Bind Human CD27 And Uses ThereofNov 23, 2021 · US 11,180,566Granted
- Anti-alk Antibodies And Methods For Use ThereofAug 17, 2021 · US 11,091,559Granted
- ANTI-PD-L1 Antibodies And Methods Of Use ThereofJul 1, 2021 · Application 17047656Pending
- Agonistic Antibodies That Bind CD40May 20, 2021 · Application 17145052Pending
- Methods Of Inducing Or Enhancing An Immune Response Comprising Administering Agonistic ANTI-CD40 AntibodiesMar 9, 2021 · US 10,941,201Granted
- Nucleic Acids Encoding Agonistic Antibodies That Bind CD40Dec 15, 2020 · US 10,865,244Granted
- Methods Of Treating By Administering Anti-kit AntibodiesOct 6, 2020 · US 10,793,639Granted
- Methods Of Treating By Administering Anti-kit AntibodiesSep 22, 2020 · US 10,781,267Granted
- Treatment Of Eosinophil Or Mast Cell Related DisordersSep 15, 2020 · US 10,774,146Granted
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentJun 2, 2020 · US 10,668,152Granted
- Agonistic Antibodies That Bind CD40Apr 28, 2020 · US 10,633,444Granted
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentJan 23, 2020 · Application 16505288Pending
- Vaccine CompositionsDec 5, 2019 · Application 16244358Pending
- Use Of ANTI-PD-1 Antibody In Combination With ANTI-CD27 Antibody In Cancer TreatmentAug 27, 2019 · US 10,392,442Granted
Recent research by its founders
- Abstract A052: Safety, immunogenicity and resistance of <i>in situ</i> Immunomodulation with CDX-301, radiotherapy, CDX-1140, and Poly-ICLC in patients with unresectable and metastatic solid tumors: a phase 1 trial20260 cites
- Data from IL10R Inhibition Induces Neutrophil Tumoricidal Activity20260 cites
- Figure S1 from IL10R Inhibition Induces Neutrophil Tumoricidal Activity20260 cites
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Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .