BIOTISSUE HOLDINGS INC.
HC-HA/PTX3, a biologic therapeutic derived from amniotic membrane components (hyaluronic acid, heavy chain 1, and pentraxin 3) that prevents proliferative vitreoretinopathy by inhibiting retinal pigme
- Sector
- Medtech
- Total capital
- $1.3M
- Federal grants
- $1.3M
- 2 awards · 2015–2016
- Rank in peer group#22 of 30
- Private capital raised
- None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 5
- 16 pending · first 2023
- Rank in peer group#5 of 30
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · Prevention of Proliferative Vitreoretinopathy by HC HA PTX$1M
- Federal grantHealth and Human S · Phase I · Prevention of Proliferative Vitreoretinopathy by HC-HA/PTX3$287K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 30 peers
Line = medianMedtech · Molecule
- Federal grantsBelow median
- Granted patents#5 · top 17%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
No founders are linked to this company yet.
Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.
Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026
Claim this profile to add your teamWhat it has protected
USPTO · 5 granted of 21- PendingApparatuses And Methods For Treating Ophthalmic Diseases And DisordersUSPTOApplication 19400523
- GrantedCompositions And Methods Relating To Pooled Fetal Support TissueUSPTOUS 12,558,379
- GrantedCompositions Of Morselized Umbilical Cord And/or Amniotic Membrane And Methods Of Use ThereofUSPTOUS 12,551,510
Show all 21 patent records
- Apparatuses And Methods For Treating Ophthalmic Diseases And DisordersJul 2, 2026 · Application 19400523Pending
- Compositions And Methods Relating To Pooled Fetal Support TissueFeb 24, 2026 · US 12,558,379Granted
- Compositions Of Morselized Umbilical Cord And/or Amniotic Membrane And Methods Of Use ThereofFeb 17, 2026 · US 12,551,510Granted
- Compositions, Devices, And Methods Relating To Use Of An Amniotic Membrane Fetal Tissue ProductFeb 12, 2026 · Application 19353469Pending
- Apparatuses And Methods For Treating Ophthalmic Diseases And DisordersDec 30, 2025 · US 12,508,349Granted
- Methods Of Modulating Bone RemodelingAug 26, 2025 · US 12,397,086Granted
- Methods Of Using Umbilical Cord Products For Treatment Of Ocular Surface DisordersJan 4, 2024 · Application 17914691Pending
- Methods For Processing Fetal Support TissueDec 14, 2023 · Application 18033470Pending
- Fetal Support Tissue Products And Methods Of UseNov 16, 2023 · Application 18201119Pending
- Umbilical Cord ProductsOct 5, 2023 · Application 18133961Pending
- Compositions Containing HC-HA/PTX3 Complexes And Methods Of Use ThereofSep 7, 2023 · Application 18051796Pending
- Fetal Support Tissue Products And Methods Of UseJul 25, 2023 · US 11,707,492Granted
- Methods Of Promoting VasculogenesisJun 8, 2023 · Application 17620650Pending
- Methods Of Killing Or Inhibiting The Growth Of Cancer CellsMar 16, 2023 · Application 17798421Pending
- Compositions And Methods For Preventing The Proliferation And Epithelial-mesenchymal Transition Of Epithelial CellsJun 9, 2022 · Application 17675887Pending
- Methods Of Cellular ReprogrammingDec 16, 2021 · Application 17291070Pending
- Compositions, Devices, And Methods Relating To Use Of An Amniotic Membrane Fetal Tissue ProductApplication PCTUS2025031892Pending
- Compositions And Methods Relating To Pooled Fetal Support TissueApplication 63334283Pending
- Methods For Processing Fetal Support TissueApplication PCTUS2021056518Pending
- Compositions, Devices, And Methods Relating To Use Of An Amniotic Membrane Fetal Tissue ProductApplication 63655526Pending
- Compositions And Methods Relating To Pooled Fetal Support TissueApplication PCTUS2023019602Pending
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Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
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- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .