AVEDRO INC
Corneal cross-linking and glaucoma/retinal disease therapeutics and devices
- Sector
- Medtech
- Headquarters
- WALTHAM, MA
- Latest Form D
- $25M, May 2018
- Total capital
- $143M
- Federal grants
- $869K
- 3 awards · 2003
- 3.0× sector median 1 award
- Private capital raised
- $142M
- 8 Form D · last May 2018
- 102 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 22
- 18 pending · first 2022
- Rank in peer group#51 of 1112
Capital timeline
Latest events
- Private capital raisedForm D · SEC · 8th filing$25M
- Private capital raisedForm D · SEC · 7th filing$12M
- Private capital raisedForm D · SEC · 6th filing$16.5M
- Private capital raisedForm D · SEC · 5th filing$6.5M
- Private capital raisedForm D · SEC · 4th filing$41.9M
- Private capital raisedForm D · SEC · 3rd filing$25.5M
- Private capital raisedForm D · SEC · 2nd filing$4.6M
- Private capital raisedForm D · SEC · 1st filing$10M
Show 3 earlier federal awards
- Federal grantHealth and Human S · Phase II · Commercialization of microwave thermokeratoplasty$117K
- Federal grantHealth and Human S · Phase II · Commercialization of microwave thermokeratoplasty$373K
- Federal grantHealth and Human S · Phase II · Commercialization of microwave thermokeratoplasty$379K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Federal first
68months
from AVEDRO INC’s first federal award to its first private round.
- First federal award · Sep 2003
- Health and Human S · $379K
- First Form D · May 2009
- $10M · 1st Form D
- Awards before first raise
- 3 awards
An association in public records, not a cause or a prediction.
Standing among 1112 peers
Line = medianMedtech · Device
- Granted patents#51 · top 5%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- David F. MullerResearcherExecutive Officer, DirectorLinked by $379K in grants as PI
- Anthony J. NataleDirectorNamed in SEC Form D filings
- Brian J. RobertsExecutive OfficerNamed in SEC Form D filings
- David J. BerryDirectorNamed in SEC Form D filings
- David J. MayerDirectorNamed in SEC Form D filings
- Donald ZurbayDirectorNamed in SEC Form D filings
Show all 23 people
- Doug Carl ColeDirectorNamed in SEC Form D filings
- Garheng KongDirectorNamed in SEC Form D filings
- GILBERT H. KLIMANDirectorNamed in SEC Form D filings
- Hongbo LuDirectorNamed in SEC Form D filings
- Jason J. HongDirectorNamed in SEC Form D filings
- Jeff J. DykanDirectorNamed in SEC Form D filings
- Jonathan SilversteinDirectorNamed in SEC Form D filings
- Joseph J. MandatoDirectorNamed in SEC Form D filings
- Michael Carl BighamDirectorNamed in SEC Form D filings
- M. Carl Johnson, IIIDirectorNamed in SEC Form D filings
- PAUL H. BAVIERExecutive OfficerNamed in SEC Form D filings
- Philip J. FerneauDirectorNamed in SEC Form D filings
- Reza ZadnoExecutive Officer, DirectorNamed in SEC Form D filings
- Rhonda J. BraceyExecutive OfficerNamed in SEC Form D filings
- ROBERT H. PALMISANODirectorNamed in SEC Form D filings
- Steve J. BlinnExecutive OfficerNamed in SEC Form D filings
- TOM H. GRIFFINExecutive OfficerNamed in SEC Form D filings
What it has protected
USPTO · 22 granted of 40- GrantedSystems And Methods For Applying And Monitoring Eye TherapyUSPTOUS 12,697,505
- GrantedCompounds and Compositions for Eye TreatmentsUSPTOUS 12,673,925
- GrantedSystems And Methods For Treating An Eye With A Mask DeviceUSPTOUS 12,636,185
Show all 40 patent records
- Systems And Methods For Applying And Monitoring Eye TherapyAug 4, 2026 · US 12,697,505Granted
- Compounds and Compositions for Eye TreatmentsJul 7, 2026 · US 12,673,925Granted
- Systems And Methods For Treating An Eye With A Mask DeviceMay 26, 2026 · US 12,636,185Granted
- Systems And Methods For Eye Tracking During Eye TreatmentFeb 12, 2026 · Application 18779976Pending
- Systems And Methods For Determining Cross-linking Distribution In A Cornea And/or Structural Characteristics Of A CorneaJan 27, 2026 · US 12,533,021Granted
- Systems And Methods For Cross-linking Treatments Of An EyeJan 1, 2026 · Application 19316793Pending
- Systems And Methods For Determining Cross-linking Distribution In A Cornea And/or Structural Characteristics Of A CorneaJan 1, 2026 · Application 19320552Pending
- Systems And Methods Treating For Corneal Ectatic DisordersDec 25, 2025 · Application 19310583Pending
- Systems And Methods For Cross-linking Treatments Of An EyeDec 18, 2025 · Application 19315130Pending
- Compounds And Compositions For Eye TreatmentsDec 11, 2025 · Application 19244221Pending
- Bis(diazirine) Derivatives As Photo-crossslinker For Treating Corneal Ectatic DisordersNov 13, 2025 · Application 19217151Pending
- Systems And Methods Treating For Corneal Ectatic DisordersOct 28, 2025 · US 12,453,652Granted
- Systems And Methods For Cross-linking Treatments Of An EyeSep 30, 2025 · US 12,427,062Granted
- Systems And Methods For Cross-linking Treatments Of An EyeSep 23, 2025 · US 12,420,072Granted
- Formulations For Eye TreatmentsAug 14, 2025 · Application 19190472Pending
- Bis(diazirine) Derivatives As Photo-crosslinker For Treating Corneal Ectatic DisordersJul 1, 2025 · US 12,344,598Granted
- Formulations For Eye TreatmentsMay 27, 2025 · US 12,311,025Granted
- Photoactivation Systems And Methods For Corneal Cross-linking TreatmentsMay 22, 2025 · Application 19030052Pending
- Systems And Methods For Generating Patient-specific Corneal Cross- Linking Treatment PatternsMay 22, 2025 · Application 19030228Pending
- Systems And Methods For Treatments Of An Eye With A PhotosensitizerMay 22, 2025 · Application 19030447Pending
- Systems and Methods for Generating Patient-Specific Corneal Cross-Linking Treatment PatternsMay 6, 2025 · US 12,293,513Granted
- Systems And Methods For Eye Tracking During Eye TreatmentMar 6, 2025 · Application 18951035Pending
- Systems And Methods For Cross-linking Treatments Of An EyeMar 6, 2025 · Application 18953999Pending
- Systems And Methods For Treatments Of An Eye With A PhotosensitizerFeb 4, 2025 · US 12,214,039Granted
- Systems and Methods for Cross-Linking Treatments of an EyeDec 24, 2024 · US 12,171,691Granted
- Systems and Methods for Eye Tracking During Eye TreatmentNov 19, 2024 · US 12,144,546Granted
- Systems And Methods For Photoactivating A Photosensitizer Applied To An EyeNov 7, 2024 · Application 18775674Pending
- Photoactivation Systems And Methods For Corneal Cross-linking TreatmentsSep 12, 2024 · Application 18663943Pending
- Systems And Methods For Photoactivating A Photosensitizer Applied To An EyeAug 27, 2024 · US 12,070,618Granted
- Systems And Methods For Eye Tracking During Eye TreatmentJul 23, 2024 · US 12,042,433Granted
- Photoactivation Systems And Methods For Corneal Cross-linking TreatmentsJun 25, 2024 · US 12,016,794Granted
- Systems And Methods For Determining Cross-linking Distribution In A Cornea And/or Structural Characteristics Of A CorneaJun 11, 2024 · US 12,004,811Granted
- Bioresorbable Corneal ImplantsApr 4, 2024 · Application 18539423Pending
- Micro-devices For Treatment Of An EyeJan 11, 2024 · Application 18471950Pending
- Bioresorbable Corneal ImplantsJan 9, 2024 · US 11,864,990Granted
- Photoactivation Systems And Methods For Corneal Cross-linking TreatmentsNov 2, 2023 · Application 18313078Pending
- Micro-devices For Treatment Of An EyeSep 26, 2023 · US 11,766,356Granted
- Photoactivation Systems And Methods For Corneal Cross-linking TreatmentsMay 9, 2023 · US 11,642,244Granted
- Systems And Methods For Determining Cross-linking Distribution In A Cornea And/or Structural Characteristics Of A CorneaDec 20, 2022 · US 11,529,050Granted
- Systems And Methods For Cross-linking Treatments Of An EyeAug 9, 2022 · US 11,406,805Granted
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Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .