APPLIED BIOTECHNOLOGY INSTITUTE

Biotech · Private

Oral Lyme disease vaccine using recombinant maize to express Borrelia burgdorferi OspA antigen

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Updated Oct 23, 2026

Sector: Biotech
Total capital: $1.9M

Federal grants: $1.4M; 9 awards · 2010–2022; Rank in peer group#142 of 326
Private capital raised: None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
Federal contracts: $450K; 1 award · Health and Human S; Rank in Biotech#235 of 4373
Granted patents: 5; 12 pending · first 2016; Rank in peer group#29 of 326

Capital timeline

Latest events

Feb 2022Federal grantHealth and Human S · Phase I · Low-cost Production of a Vaccine for Lyme Disease in Maize$311K
Mar 2021Federal grantHealth and Human S · Phase I · Low-cost Production of a Vaccine for Lyme Disease in Maize$283K
Jul 2019Federal grantAgriculture · Orally-delivered Fish Vaccines$100K
Jul 2019Federal grantAgriculture · Production Of A Candidate Vaccine For Avian Coccidiosis In Maize$100K
May 2017Federal grantHealth and Human S · Phase I · Production of stabilized trimeric HIV Env protein in maize$150K
Aug 2016Federal contractHealth and Human S · Igf::ot::igf Title - A Mucosal Prophylactic Vaccine Against Coccidioidomycosis$450K
Aug 2016Federal grantHealth and Human S · Phase I · Production of immunogenic Ebola GP protein in maize$147K

Show 3 earlier federal awards

Apr 2016Federal grantHealth and Human S · Phase I · Improving the efficacy of hepatitis B prophylactic vaccines$147K
May 2012Federal grantAgriculture · Use Of Cellulase-containing Maize To Lower Cost Of Forest Products Biofuels$100K
Jun 2010Federal grantAgriculture · Synergy Of Plant-produced Enzymes To Convert Forest Products Into Biofuels$90K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Standing among 326 peers

Line = median

Biotech · Molecule

Federal grants#142 · top 44%
Granted patents#29 · top 9%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

No founders are linked to this company yet.

Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.

Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026

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What it has protected

USPTO · 5 granted of 17

Feb 6, 2025PendingExpression Of Borrelia Burgdorferi Outer Surface Protein A In Plants And Plant Produced Vaccine For SameUSPTOApplication 18678214
Jan 5, 2023PendingEXPRESSION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2) SPIKE PROTEIN SEQUENCES IN PLANTS AND PLANT PRODUCED VACCINE FOR SAMEUSPTOApplication 17808901
Jun 23, 2022PendingMethods To Increase Antigenicity Of Membrane-bound Polypeptides Produced In PlantsUSPTOApplication 17455871

Show all 17 patent records

Expression Of Borrelia Burgdorferi Outer Surface Protein A In Plants And Plant Produced Vaccine For SameFeb 6, 2025 · Application 18678214Pending
EXPRESSION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2) SPIKE PROTEIN SEQUENCES IN PLANTS AND PLANT PRODUCED VACCINE FOR SAMEJan 5, 2023 · Application 17808901Pending
Methods To Increase Antigenicity Of Membrane-bound Polypeptides Produced In PlantsJun 23, 2022 · Application 17455871Pending
Plant-produced Vaccine Comprising An AG2 Polypeptide From CoccidioidesSep 21, 2021 · US 11,124,799Granted
Methods And Compositions To Increase Immune Response To VaccinesAug 17, 2021 · US 11,090,380Granted
Method of increasing expression of nucleic acid molecules in plants using multiple transcription unitsJun 4, 2019 · US 10,308,948Granted
Methods To Increase Antigenicity Of Membrane-bound Polypeptides Produced In PlantsJan 24, 2019 · Application 16156427Pending
Methods To Increase Antigenicity Of Membrane-bound Polypeptides Produced In PlantsDec 11, 2018 · US 10,150,970Granted
Expression of Butyrylcholinesterase in plantsApr 6, 2017 · Application 15194740Pending
Pericarp tissue preferred regulatory region and method of using sameSep 13, 2016 · US 9,441,232Granted
Methods And Compositions To Increase Immune Response To VaccinesApplication 62680412Pending
Expression Of Borrelia Burgdorferi Outer Surface Protein A In Plants And Plant Produced Vaccine For SameApplication 63516625Pending
An Embryo Preferred Promoter And Method Of Using SameApplication PCTUS2005016232Pending
EXPRESSION OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2) SPIKE PROTEIN SEQUENCES IN PLANTS AND PLANT PRODUCED VACCINE FOR SAMEApplication 63202816Pending
GLOBULIN-1 Promoter And Method Of Using SameApplication PCTUS2005009370Pending
Expression Of Eimeria Sequences In Plants And Plant Produced Vaccine For SameApplication 63266112Pending
Expression Of Valley Fever Sequences In Plants And Plant Produced Vaccines For SameApplication 62686921Pending

Cocrystal Pharma, Inc.Similar federal contract value in Biotech · $498K in contracts
Mirum PharmaceuticalsSimilar federal contract value in Biotech · $460K in contracts
ARIMA GENOMICS, INC.Similar federal contract value in Biotech · $457K in contracts
Nanode Therapeutics, Inc.Similar federal contract value in Biotech · $441K in contracts
Rejuvenics Technologies LLCSimilar federal contract value in Biotech · $438K in contracts
Litron Laboratories LtdSimilar federal contract value in Biotech · $426K in contracts

Regulatory activity · Biotech

Sector-level, not company-level

07 Jul 2026New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
30 Jun 2026Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
30 Jun 2026Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
29 Jun 2026Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
26 Jun 2026Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
26 Jun 2026Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through Oct 23, 2026. SBIR and STTR awards through Oct 21, 2026.