APIE THERAPEUTICS INC
oral anti-fibrotic small molecule targeting the apelin/APJ signaling pathway for systemic sclerosis treatment
- Sector
- Biotech
- Headquarters
- Cary, NC
- Founded
- 2020
- Latest Form D
- $100K, Sep 2020
- Total capital
- $1M
- Federal grants
- $905K
- 2 awards · 2023
- Rank in peer group#299 of 502
- Private capital raised
- $100K
- 1 Form D · last Sep 2020
- 73 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- None on recordNo USPTO grants. Applications publish after 18 months.
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase I · Development of Novel Small Molecule Anti-Fibrotic Agent for the Treatment of Systemic Scleroderma$452K
- Federal grantHealth and Human S · Phase I · Development of Novel Small Molecule Anti-Fibrotic Agent for the Treatment of Systemic Scleroderma$452K
- Private capital raisedForm D · SEC · 1st filing$100K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 502 peers
Line = medianBiotech · Molecule
- Federal grantsBelow median
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Esther AlegriaResearcherExecutive Officer, Director, PromoterLinked by $452K in grants as PI
- Maureen O'ConnorDirectorNamed in SEC Form D filings
- Peter JohnstonDirectorNamed in SEC Form D filings
- Seth HetheringtonDirectorNamed in SEC Form D filings
- Vinay TannanDirectorNamed in SEC Form D filings
What it has protected
No granted patents are on record.
USPTO usually publishes applications 18 months after filing, so recent applications may not be visible yet. Patents assigned under a different entity name won’t match.
Checked: USPTO granted patents and published applications · Oct 23, 2026
Related companies, and why
- HB THERAPEUTICS, INC.Similar federal contract value in Biotech · null in contracts
- Mulberry Biotherapeutics, Inc.Similar federal contract value in Biotech · null in contracts
- NUAGO THERAPEUTICS INCSimilar federal contract value in Biotech · null in contracts
- ANNEXON, INC.Similar federal contract value in Biotech · null in contracts
- SYNTAXISBIO, INC.Similar federal contract value in Biotech · null in contracts
- EPITOR THERAPEUTICS, INC.Similar federal contract value in Biotech · null in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .