APHIOS CORPORATION
Extended-release nanoformulated combination of naltrexone and cannabidiol in biodegradable polymer nanospheres for opioid use disorder treatment
- Sector
- Biotech
- Headquarters
- Woburn, MA
- Total capital
- $11.2M
- Federal grants
- $10.5M
- 14 awards · 2015–2025
- Rank in peer group#47 of 514
- Private capital raised
- None on recordNo Form D filings on SEC EDGAR. Some raises are not filed.
- Federal contracts
- $723K
- 5 awards · Defense, Health and Human S
- Rank in Biotech#212 of 4373
- Granted patents
- 5
- 14 pending · first 2015
- Rank in peer group#71 of 514
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase I · Botanical Drug for Chemotherapy Induced Nausea and Vomiting$416K
- Federal grantHealth and Human S · Phase I · Development of a Novel Alzheimer's Disease Therapeutic$505K
- Federal grantHealth and Human S · Phase I · Double-Encapsulated mRNA Vaccine for COVID-19$300K
- Federal grantHealth and Human S · Phase I · Combination Therapeutic for Chronic Opioid Use Disorder Relapse$336K
- Federal grantHealth and Human S · Phase I · Double-Encapsulated mRNA Vaccine for COVID-19$300K
- Federal grantHealth and Human S · Phase II · CFI Pathogen Inactivation of Human Plasma Units$1.8M
- Federal grantHealth and Human S · Phase II · CFI Pathogen Inactivation of Human Plasma Units$3.3M
Show 11 earlier federal awards
- Federal grantHealth and Human S · Phase II · CFI Pathogen Inactivation of Human Plasma Units$600K
- Federal contractHealth and Human S · Igf::ot::igf Critical Fluid Nanosomes For Effective Targeted Delivery And Manufacture Of Sirna-based Therapeutics$300K
- Federal grantHealth and Human S · Phase I · Purging Latent HIV Reservoirs through a Combination HIV Therapeutic$575K
- Federal grantHealth and Human S · Phase I · Purging Latent HIV Reservoirs through a Combination HIV Therapeutic$50K
- Federal grantHealth and Human S · Phase II · Development of cGMP Manufacturing Process for CBD$742K
- Federal grantHealth and Human S · Phase I · Purging Latent HIV Reservoirs through a Combination HIV Therapeutic$463K
- Federal grantHealth and Human S · Phase II · Development of cGMP Manufacturing Process for CBD$742K
- Federal contractHealth and Human S · Tas:: 75 0896::TAS SBIR Phase I Topic Nccam 002$94K
- Federal contractHealth and Human S · SBIR Phase 1 Topic 43$149K
- Federal contractHealth and Human S · 402 - Rfp: N43-CM-87007-68 Topic 251: Development Of Anticancer Agents Requestor: Ali Andalibi Vendor: Aphois Corp$150K
- Federal contractDefense · Dried Marine Microorganisms Fractions$30K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
1 record has no date or no amount, so it isn’t placed on the timeline.
Standing among 514 peers
Line = medianBiotech · Molecule
- Federal grants#47 · top 9%
- Granted patents#71 · top 14%
- Linked publications#95 · top 18%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
No founders are linked to this company yet.
Founders appear once a person is matched to the company through its own patents, grants or filings. We never infer people from social profiles.
Checked: USPTO inventors; federal award principal investigators; SEC Form D related persons · Oct 23, 2026
Claim this profile to add your teamWhat it has protected
USPTO · 5 granted of 19- PendingMethods For and Products From Encapsulation of Drugs in Nanoparticles in a Microgravity EnvironmentUSPTOApplication 18634819
- PendingMethods For And Products From Encapsulation Of Drugs In Nanoparticles In A Microgravity EnvironmentUSPTOApplication 17221831
- PendingMethods And Products For Treating Folic Acid Deficiency And Morning SicknessUSPTOApplication 17311633
Show all 19 patent records
- Methods For and Products From Encapsulation of Drugs in Nanoparticles in a Microgravity EnvironmentAug 1, 2024 · Application 18634819Pending
- Methods For And Products From Encapsulation Of Drugs In Nanoparticles In A Microgravity EnvironmentOct 6, 2022 · Application 17221831Pending
- Methods And Products For Treating Folic Acid Deficiency And Morning SicknessJan 20, 2022 · Application 17311633Pending
- Bryoid Compositions, Methods Of Making And Use ThereofMar 23, 2021 · US 10,954,248Granted
- Combination Therapeutics And Methods For The Treatment Of Neurodegenerative And Other DiseasesNov 10, 2020 · US 10,828,276Granted
- Combination Hiv TherapeuticDec 3, 2019 · US 10,493,030Granted
- Formulations and Compositions of Vitamin D Analogs for Treating and Preventing Cancer and other DiseasesApr 16, 2019 · US 10,258,635Granted
- Apparatus And Methods For Making Nanosomes Loaded With Nucleic AcidSep 27, 2018 · Application 15989996Pending
- Formulations And Compositions Of Vitamin D Analogs For Treating And Preventing Cancer And Other DiseasesJan 14, 2016 · Application 14329923Pending
- Bryoid Compositions, Methods Of Making And Use ThereofOct 15, 2015 · Application 14647237Pending
- Drug Delivery System And Method For The Treatment Of Neuro-degenerative DiseaseMay 19, 2015 · US 9,034,347Granted
- Methods, Kits And Compositions For Inactivation Of Viral Agents In Whole Blood And Red Blood Cell ConcentratesMar 20, 2014 · Application 14019671Pending
- Dosage Form, And Methods Of Making And Using The Same, To Produce Immunization In Animals And HumansMay 16, 2013 · Application 13656175Pending
- Methods And Products For Treating Folic Acid Deficiency And Morning SicknessApplication PCTUS2019064744Pending
- Combination Therapeutics And Methods For The Treatment Of Neurodegenerative And Other DiseasesApplication PCTUS2013072076Pending
- Bryoid Compositions, Methods Of Making And Use ThereofApplication PCTUS2013072070Pending
- Dosage Forms For Improving Organ Transplantation, Graft Versus Host Disease And Stem Cells TransplantsApplication PCTUS2020022397Pending
- Combination Hiv TherapeuticApplication 62165444Pending
- Combination Hiv TherapeuticApplication PCTUS2016033766Pending
Recent research by its founders
- Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation202212 cites
- Nanoparticle-Encapsulated Bryostatin-1 Activates α-Secretase and PKC Isoforms In vitro and Facilitates Acquisition and Retention of Spatial Learning in an Alzheimer's Disease Mouse Model20215 cites
- Interferon-gamma depresses human intestinal smooth muscle cell contractility: Relevance to inflammatory gut motility disturbances201916 cites
Related companies, and why
- GEN1E LIFESCIENCES INC.Similar federal contract value in Biotech · $749K in contracts
- GALEN BIOTECHNOLOGIES, LLCSimilar federal contract value in Biotech · $727K in contracts
- KromaTiD, Inc.Similar federal contract value in Biotech · $726K in contracts
- PREDICTIVE BIOLOGYSimilar federal contract value in Biotech · $654K in contracts
- Perfinity Biosciences, Inc.Similar federal contract value in Biotech · $649K in contracts
- iXpressGenes, Inc.Similar federal contract value in Biotech · $614K in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .