Antheia, Inc.
Biosynthetic production of naloxone, naltrexone, and buprenorphine via yeast fermentation
- Sector
- Biotech
- Headquarters
- MENLO PARK, CA
- Founded
- 2013
- Latest Form D
- $9.2M, Sep 2018
- Total capital
- $19.7M
- Federal grants
- $2.4M
- 6 awards · 2016–2018
- Rank in peer group#458 of 514
- Private capital raised
- $17.4M
- 3 Form D · last Sep 2018
- 98 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 13
- 25 pending · first 2020
- Rank in peer group#18 of 514
Capital timeline
Latest events
- Private capital raisedForm D · SEC · 3rd filing$9.2M
- Federal grantNSF · Phase II · SBIR Phase II: A complete bioprocess for medicinal plant opioids$1.2M
- Private capital raisedForm D · SEC · 2nd filing$6.2M
- Federal grantHealth and Human S · Phase I · Microbial biosynthesis of opioid antagonists a novel low cost method for producing addiction pharmacotherapies$225K
- Federal grantHealth and Human S · Phase I · Microbial biosynthesis of opioid antagonists: a novel, low-cost method for producing addiction pharmacotherapies$225K
- Federal grantHealth and Human S · Phase I · Biosynthesis of novel and natural plant alkaloid compounds for drug production and discovery$225K
- Federal grantNSF · Phase I · SBIR Phase I: Engineering biocatalysts for biomanufacturing of medicinal opioids$225K
- Private capital raisedForm D · SEC · 1st filing$2M
Show 1 earlier federal award
- Federal grantNSF · Phase I · SBIR Phase I: Production of plant alkaloid therapeutics via fermentation of engineered yeast$225K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 514 peers
Line = medianBiotech · Molecule
- Federal grantsBelow median
- Granted patents#18 · top 4%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Christina D. SmolkeResearcherExecutive Officer, DirectorLinked by 5 patents
- Catherine D. ThodeyResearcherDirectorLinked by $225K in grants as PI
- Ram D. ShriramDirectorNamed in SEC Form D filings
- Valerie D. MinassianExecutive OfficerNamed in SEC Form D filings
What it has protected
USPTO · 13 granted of 38- PendingMethods Of Producing Morphinan Alkaloids And DerivativesUSPTOApplication 19338793
- GrantedMethods Of Producing Morphinan Alkaloids And DerivativesUSPTOUS 12,674,185
- PendingCompositions And Methods For Making Benzylisoquinoline Alkaloids, Morphinan Alkaloids, Thebaine, And Derivatives ThereofUSPTOApplication 19186191
Show all 38 patent records
- Methods Of Producing Morphinan Alkaloids And DerivativesAug 27, 2026 · Application 19338793Pending
- Methods Of Producing Morphinan Alkaloids And DerivativesJul 7, 2026 · US 12,674,185Granted
- Compositions And Methods For Making Benzylisoquinoline Alkaloids, Morphinan Alkaloids, Thebaine, And Derivatives ThereofMay 7, 2026 · Application 19186191Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApr 16, 2026 · Application 19116895Pending
- Compositions And Methods For Making Benzylisoquinoline Alkaloids, Morphinan Alkaloids, Thebaine, And Derivatives ThereofSep 16, 2025 · US 12,416,029Granted
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsMay 1, 2025 · Application 18962453Pending
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsDec 31, 2024 · US 12,180,525Granted
- Polynucleotides And Polypeptides Useful For Making Alkaloid CompoundsDec 24, 2024 · US 12,173,035Granted
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesMar 28, 2024 · Application 18253585Pending
- Methods Of Producing Morphinan Alkaloids And DerivativesJan 30, 2024 · US 11,884,949Granted
- Compositions And Methods For Making (r)-reticuline And Precursors ThereofJan 4, 2024 · Application 18179035Pending
- Neopinone Isomerase And Methods Of UsingNov 9, 2023 · Application 18145608Pending
- Compositions and Methods For Making (R)-Reticuline and Precursors ThereofMar 28, 2023 · US 11,613,770Granted
- Neopinone Isomerase And Methods Of UsingJan 24, 2023 · US 11,560,578Granted
- Polynucleotides And Polypeptides Useful For Making Alkaloid CompoundsOct 25, 2022 · US 11,479,586Granted
- Engineered Benzylisoquinoline Alkaloid Epimerases And Methods Of Producing Benzylisoquinoline AlkaloidsAug 30, 2022 · US 11,427,827Granted
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsJul 26, 2022 · US 11,396,668Granted
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesMay 26, 2022 · Application 17486274Pending
- Compositions And Methods For Making Benzylisoquinoline Alkaloids, Morphinan Alkaloids, Thebaine, And Derivatives ThereofOct 12, 2021 · US 11,142,780Granted
- Compositions And Methods For Making Noscapine And Synthesis Intermediates ThereofMay 27, 2021 · Application 17004759Pending
- Microorganisms and Methods in the Fermentation of Benzylisoquinoline AlkaloidsOct 15, 2020 · Application 16754003Pending
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsAug 11, 2020 · US 10,738,335Granted
- Engineered Benzylisoquinoline Alkaloid Epimerases And Methods Of Producing Benzylisoquinoline AlkaloidsJan 28, 2020 · US 10,544,420Granted
- Methods Of Producing Morphinan Alkaloids And DerivativesApplication PCTUS2019017357Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication 63116097Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication PCTUS2021059980Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication 63377672Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication PCTUS2023075653Pending
- Engineered Benzylisoquinoline Alkaloid Epimerases And Methods Of Producing Benzylisoquinoline AlkaloidsApplication PCTUS2018045222Pending
- Methods Of Producing Morphinan Alkaloids And DerivativesApplication 62628264Pending
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsApplication PCTUS2017057237Pending
- Microorganisms And Methods In The Fermentation Of Benzylisoquinoline AlkaloidsApplication 62556022Pending
- Engineered Benzylisoquinoline Alkaloid Epimerases And Methods Of Producing Benzylisoquinoline AlkaloidsApplication 62541038Pending
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsApplication 62473215Pending
- Methods Of Producing Nor-opioid And Nal-opioid Benzylisoquinoline AlkaloidsApplication 62409837Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication PCTUS2020024735Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication 17442289Pending
- Methods Of Improving Production Of Morphinan Alkaloids And DerivativesApplication 62824252Pending
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Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .