ALUME BIOSCIENCES, INC.
Fluorescent imaging agent (bevonescein) that illuminates nerves during surgery
- Sector
- Medtech
- Headquarters
- San Diego, CA
- Founded
- 2017
- Latest Form D
- $110K, Apr 2026
- Total capital
- $37.9M
- Federal grants
- $9.2M
- 6 awards · 2019–2024
- Rank in peer group#7 of 41
- Private capital raised
- $28.7M
- 6 Form D · last Apr 2026
- 7 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 3
- 14 pending · first 2024
- Rank in peer group#8 of 41
Capital timeline
Latest events
- Private capital raisedForm D · SEC · 6th filing$110K
- Private capital raisedForm D · SEC · 5th filing$3.1M
- Federal grantHealth and Human S · Phase II · Development of ALM-488 for nerve and ureter visualization during abdominal surgery$866K
- Federal grantHealth and Human S · Phase II · Development of ALM-488 for nerve and ureter visualization during abdominal surgery$937K
- Private capital raisedForm D · SEC · 4th filing$12.8M
- Federal grantHealth and Human S · Phase II · Commercialization of ALM-488 for Highlighting Nerves During Image Guided Surgeries$3.4M
- Private capital raisedForm D · SEC · 3rd filing$3M
- Private capital raisedForm D · SEC · 2nd filing$4M
- Private capital raisedForm D · SEC · 1st filing$5.8M
Show 3 earlier federal awards
- Federal grantHealth and Human S · Phase II · Development of Fluorescent Probes for Highlighting Nerves During Image Guided Surgeries$1.2M
- Federal grantHealth and Human S · Phase II · Development of Fluorescent Probes for Highlighting Nerves During Image Guided Surgeries$2.5M
- Federal grantHealth and Human S · Phase I · Development of Fluorescent Probes for Highlighting Nerves During Image Guided Surgeries$300K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Federal first
3months
from ALUME BIOSCIENCES, INC.’s first federal award to its first private round.
- First federal award · Apr 2019
- Health and Human S · $300K
- First Form D · Jul 2019
- $5.8M · 1st Form D
- Awards before first raise
- 1 award
An association in public records, not a cause or a prediction.
Standing among 41 peers
Line = medianMedtech · Molecule
- Federal grants#7 · top 17%
- Granted patents#8 · top 20%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- Quyen T. NguyenResearcherExecutive Officer, DirectorLinked by 2 patents
- Brett T BermanResearcherExecutive OfficerLinked by 1 patent
- Dan T. BradburyDirectorNamed in SEC Form D filings
- James SchmidtExecutive OfficerNamed in SEC Form D filings
- Jean-Pierre T MillionDirectorNamed in SEC Form D filings
- Jean-Pierre MillonDirectorNamed in SEC Form D filings
Show all 9 people
- Kaveri ParkerExecutive OfficerNamed in SEC Form D filings
- Kim T. KamdarDirectorNamed in SEC Form D filings
- Magda T MarquetDirectorNamed in SEC Form D filings
What it has protected
USPTO · 3 granted of 17- GrantedMethods And Systems Using Peptides For Targeting And Mapping Human Nerves In Image Guided Surgery, Diagnostics And Therapeutic DeliveryUSPTOUS 12,533,425
- GrantedOptical Filter Holder And AdapterUSPTOUS D1,089,368
- PendingMethods And Compositions For Visualizing A Ureter In A Surgical ProcedureUSPTOApplication 18780117
Show all 17 patent records
- Methods And Systems Using Peptides For Targeting And Mapping Human Nerves In Image Guided Surgery, Diagnostics And Therapeutic DeliveryJan 27, 2026 · US 12,533,425Granted
- Optical Filter Holder And AdapterAug 19, 2025 · US D1,089,368Granted
- Methods And Compositions For Visualizing A Ureter In A Surgical ProcedureJan 9, 2025 · Application 18780117Pending
- Methods And Compositions For Visualizing A Ureter In A Surgical ProcedureDec 10, 2024 · US 12,161,729Granted
- Nerve Targeting Peptide Conjugates And Methods Of UseJun 27, 2024 · Application 18531565Pending
- Nerve Targeting Peptides And Methods Of UseJun 27, 2024 · Application 18254565Pending
- Nerve Targeting Peptides And Methods Of UseApplication 63167572Pending
- Methods And Compositions For Visualizing A Ureter In A Surgical ProcedureApplication 63137621Pending
- Nerve Targeting Peptides And Methods Of UseApplication 63121825Pending
- Methods And Systems Using Peptides For Targeting And Mapping Human Nerves In Image Guided Surgery, Diagnostics And Therapeutic DeliveryApplication PCTUS2020055106Pending
- Fluorescein-labeled Nerve Targeting Peptide Formulations And Related MethodsApplication 19483211Pending
- Methods And Systems Using Peptides For Targeting Human Nerves In Image Guided Surgery, Diagnostics And Therapeutic DeliveryApplication 62913654Pending
- Fluorescein-labeled Nerve Targeting Peptide Formulations And Related MethodsApplication PCTUS2024028401Pending
- Fluorescein-labeled Nerve Targeting Peptide Formulations And Related MethodsApplication 63501593Pending
- Nerve Targeting Peptide Conjugates And Methods Of UseApplication 63386470Pending
- Methods And Compositions For Visualizing A Ureter In A Surgical ProcedureApplication PCTUS2022012379Pending
- Nerve Targeting Peptides And Methods Of UseApplication PCTUS2021061821Pending
Related companies, and why
- NIMA LABS, INC.Similar federal contract value in Medtech · null in contracts
- LAZARUS 3D, INC.Similar federal contract value in Medtech · null in contracts
- Alessa Therapeutics, Inc.Similar federal contract value in Medtech · null in contracts
- RICOVR HEALTHCARE INC.Similar federal contract value in Medtech · null in contracts
- LAZZARO MEDICAL, INC.Similar federal contract value in Medtech · null in contracts
- Abilitech Medical, Inc.Similar federal contract value in Medtech · null in contracts
Regulatory activity · Medtech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .