ALTO NEUROSCIENCE, INC.

MOUNTAIN VIEW, CA · Founded 2019 · Medtech · Still private

EEG-based machine learning biomarkers for psychiatric disorder stratification and treatment prediction

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Updated · altoneuroscience.com

Sector
Medtech
Headquarters
MOUNTAIN VIEW, CA
Founded
2019
Latest Form D
$50M, Oct 2025
Total capital
$197M
Federal grants
$3.2M
3 awards · 2020–2022
Rank in peer group#30 of 53
Private capital raised
$194M
5 Form D · last Oct 2025
12 months since last filing
Federal contracts
None on recordNo federal contract awards found.
Granted patents
7
33 pending · first 2025
Rank in peer group#6 of 53

Capital timeline

202020212022202320242025FEDERAL ↑EQUITY ↓Cumulative $197M$988K$1.2M$1M1st Form D$45M2nd Form D$59.3M5th Form D$50M
202020212022202320242025FEDERAL ↑EQUITY ↓Cumulative $197M$988K$1.2M$1M1st Form D$45M2nd Form D$59.3M

Latest events

  • Private capital raisedForm D · SEC · 5th filing$50M
  • Private capital raisedForm D · SEC · 4th filing$7.7M
  • Private capital raisedForm D · SEC · 3rd filing$31.9M
  • Private capital raisedForm D · SEC · 2nd filing$59.3M
  • Private capital raisedForm D · SEC · 1st filing$45M
  • Federal grantHealth and Human S · Phase II · Validating of Machine Learning-Based EEG Treatment Biomarkers in Depression$1M
  • Federal grantHealth and Human S · Phase II · Validating of Machine Learning-Based EEG Treatment Biomarkers in Depression$1.2M
Show 1 earlier federal award
  • Federal grantHealth and Human S · Phase II · Validating of Machine Learning-Based EEG Treatment Biomarkers in Depression$988K

Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.

Federal first

45months

from ALTO NEUROSCIENCE, INC.’s first federal award to its first private round.

First federal award · Feb 2020
Health and Human S · $988K
First Form D · Nov 2023
$45M · 1st Form D
Awards before first raise
3 awards

An association in public records, not a cause or a prediction.

Standing among 53 peers

Line = median

Medtech · Software

  • Federal grantsBelow median
  • Granted patents#6 · top 11%
  • Linked publications#2 · top 4%

Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.

Founders and team

Researcher links verified by same-company patents and grants
  • Amit EtkinResearcherExecutive Officer, DirectorLinked by 1 patent · $3.2M in grants as PI
  • Aaron WeaverDirectorNamed in SEC Form D filings
  • Adam SavitzExecutive OfficerNamed in SEC Form D filings
  • Andrew Nixon DreyfusDirectorNamed in SEC Form D filings
  • Chris Nixon DimitropoulosDirectorNamed in SEC Form D filings
  • Christopher Nixon CoxDirectorNamed in SEC Form D filings
Show all 13 people
  • Gwill YorkDirectorNamed in SEC Form D filings
  • Husseini Nixon ManjiDirectorNamed in SEC Form D filings
  • Michael HanleyExecutive OfficerNamed in SEC Form D filings
  • Michael Nixon LiangDirectorNamed in SEC Form D filings
  • Nicholas SmithExecutive OfficerNamed in SEC Form D filings
  • Po Yu (Jeff) ChenDirectorNamed in SEC Form D filings
  • Raymond Nixon SanchezDirectorNamed in SEC Form D filings

What it has protected

USPTO · 7 granted of 40
  • PendingCombination Therapy For A Dopamine AgonistUSPTOApplication 19653745
  • PendingPlacebo Response Prediction For Psychiatric PatientsUSPTOApplication 19537878
  • PendingEeg Montage For Facilitating Selection Of Drug Treatment In Patients Suffering From Psychiatric DisordersUSPTOApplication 19532015
Show all 40 patent records
  • Combination Therapy For A Dopamine AgonistSep 3, 2026 · Application 19653745Pending
  • Placebo Response Prediction For Psychiatric PatientsAug 13, 2026 · Application 19537878Pending
  • Eeg Montage For Facilitating Selection Of Drug Treatment In Patients Suffering From Psychiatric DisordersAug 6, 2026 · Application 19532015Pending
  • Combination Therapy For A Dopamine AgonistJun 9, 2026 · US 12,648,934Granted
  • Combination Therapy For A Dopamine AgonistMay 28, 2026 · Application 19453621Pending
  • Integration Of Molecular Mechanisms In The Striatum As A Combination Drug Strategy For The Treatment Of Psychiatric And Neurological Disorders In Which Anhedonia Or Motivation-related Dysfunction ExistsMay 21, 2026 · Application 19450399Pending
  • Anti-neurodegenerative Combinations And Use For Treatment Of Neurodegenerative DiseasesMay 12, 2026 · US 12,622,895Granted
  • Eeg Montage For Facilitating Selection Of Drug Treatment In Patients Suffering From Psychiatric DisordersApr 7, 2026 · US 12,594,028Granted
  • Method For Improving NeuroplasticityMar 5, 2026 · Application 19316824Pending
  • Combination Therapy For A Dopamine AgonistJan 13, 2026 · US 12,521,374Granted
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentJun 5, 2025 · Application 19052783Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentJun 5, 2025 · Application 19040204Pending
  • Method Of Treatment And Selection Of Patients Benefiting From Agomelatine Based On Eeg MeasurementsJun 5, 2025 · Application 19043072Pending
  • Treatment Of Psychiatric Or Neurological Disorders In Patients With Prominent Anhedonia Using Irdabisant As A Monotherapy Or In Combination With An Antipsychotic AgentMay 8, 2025 · Application 18933579Pending
  • Treatment Of Neuropsychiatric Disorders With TilivapramApr 17, 2025 · Application 18896294Pending
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentFeb 25, 2025 · US 12,233,059Granted
  • Method Of Treatment And Selection Of Patients Benefiting From Agomelatine Based On Eeg MeasurementsFeb 18, 2025 · US 12,226,375Granted
  • Method Of Treatment And Selection Of Patients Benefiting From Agomelatine Based On Eeg MeasurementsFeb 13, 2025 · Application 18670524Pending
  • Method Of Treatment And Selection Of Patients Benefiting From Agomelatine Based On Eeg MeasurementsFeb 13, 2025 · Application 18670556Pending
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentJan 28, 2025 · US 12,208,096Granted
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentJan 9, 2025 · Application 18892030Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentOct 17, 2024 · Application 18670580Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentOct 17, 2024 · Application 18670604Pending
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentSep 26, 2024 · Application 18670632Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentSep 19, 2024 · Application 18670588Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentSep 19, 2024 · Application 18670599Pending
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentSep 19, 2024 · Application 18670619Pending
  • Effective Treatment Of Depression In Patients Having Impaired Learning And/or Memory Or Certain Eeg Characteristics With A Benzylpiperazine-aminopyridine AgentJun 20, 2024 · Application 18528486Pending
  • Enhancement Of Camp Signaling As A Combination Drug Strategy For The Treatment Of Psychiatric And Neurological Disorders In Which Depressive, Anhedonia, Motivation-related Or Cognition-related Dysfunction ExistsApr 20, 2023 · Application 18063907Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentDec 8, 2022 · Application 17805374Pending
  • Integration Of Molecular Mechanisms In The Striatum As A Combination Drug Strategy For The Treatment Of Psychiatric And Neurological Disorders In Which Anhedonia Or Motivation-related Dysfunction ExistsJul 21, 2022 · Application 17648538Pending
  • Composition And Use For The Treatment Of Parkinson's Disease And Related DisordersNov 4, 2021 · Application 17279644Pending
  • Compositions And Method For Treating DepressionDec 3, 2020 · Application 16607252Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentApplication PCTUS2022032136Pending
  • Enhancement Of Camp Signaling As A Combination Drug Strategy For The Treatment Of Depression And Related ConditionsApplication PCTUS2022013197Pending
  • Integration Of Molecular Mechanisms In The Striatum As A Combination Drug Strategy For The Treatment Of Psychiatric And Neurological Disorders In Which Anhedonia Or Motivation-related Dysfunction ExistsApplication PCTUS2022013194Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentApplication 63264269Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentApplication 63263168Pending
  • Method Of Treatment Of Depressed Patients With Poor Cognition And Selection Of Other Patients Benefiting From A Benzylpiperazine-aminopyridine AgentApplication 63202254Pending
  • Integration Of Molecular Mechanisms In The Striatum As A Combination Drug Strategy For The Treatment Of Depression And Related ConditionsApplication 63199723Pending

Recent research by its founders

  • Brain Neuroplasticity Mechanisms in Psychiatric Illnesses and in the Development of Novel Treatments20263 cites
  • Childhood Maltreatment and Deviations From Normative Brain Structure: A Mega-Analysis of 3711 Individuals From the ENIGMA Major Depressive Disorder and ENIGMA Posttraumatic Stress Disorder Working Groups20261 cites
  • Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS20260 cites

Regulatory activity · Medtech

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Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.

Sources

Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.

How to read this page

Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.

Data freshness

SEC Form D filings through . SBIR and STTR awards through .