Agenebio, Inc.
Orally active small-molecule GABA-A α5 positive allosteric modulator (PAM) for mild cognitive impairment due to Alzheimer's disease
- Sector
- Biotech
- Headquarters
- Baltimore, MD
- Founded
- 2008
- Latest Form D
- $500K, Jul 2016
- Total capital
- $12M
- Federal grants
- $4.1M
- 4 awards · 2019–2021
- Rank in peer group#225 of 514
- Private capital raised
- $7.9M
- 9 Form D · last Jul 2016
- 123 months since last filing
- Federal contracts
- None on recordNo federal contract awards found.
- Granted patents
- 14
- 26 pending · first 2017
- Rank in peer group#16 of 514
Capital timeline
Latest events
- Federal grantHealth and Human S · Phase II · Structurally Diverse GABA-A a5 Positive Allosteric Modulators for Treatment of MCI due to AD$626K
- Federal grantHealth and Human S · Phase II · Structurally Diverse GABA-A a5 Positive Allosteric Modulators for Treatment of MCI due to AD$235K
- Federal grantHealth and Human S · Phase II · Structurally Diverse GABA-A a5 Positive Allosteric Modulators for Treatment of MCI due to AD$2.1M
- Federal grantHealth and Human S · Phase II · Structurally Diverse GABA-A ÃÂÃÂÃÂÃÂÃÂÃÂÃÂñ5 Positive Allosteric Modulators for Treatment of MCI due to AD$1.1M
- Private capital raisedForm D · SEC · 9th filing$500K
- Private capital raisedForm D · SEC · 8th filing$400K
- Private capital raisedForm D · SEC · 7th filing$4.1M
- Private capital raisedForm D · SEC · 6th filing$1M
- Private capital raisedForm D · SEC · 5th filing$1M
- Private capital raisedForm D · SEC · 4th filing$450K
- Private capital raisedForm D · SEC · 3rd filing$110K
- Private capital raisedForm D · SEC · 2nd filing$300K
- Private capital raisedForm D · SEC · 1st filing$50K
Node area is scaled to amount. Form D reports securities sold, which can differ from an announced round; filings are numbered in the order they were made.
Standing among 514 peers
Line = medianBiotech · Molecule
- Federal grants#225 · top 44%
- Granted patents#16 · top 3%
- Linked publications#41 · top 8%
Cumulative measures favor older companies. Rankings describe position today, not outcome. Below the median, ranks show as a band rather than a number.
Founders and team
Researcher links verified by same-company patents and grants- SHARON W. ROSENZWEIG-LIPSONResearcherExecutive OfficerLinked by $4.1M in grants as PI
- Brian F. StemmeDirectorNamed in SEC Form D filings
- CHARLES W. CLARVITDirectorNamed in SEC Form D filings
- FLOYD W. BLOOMDirectorNamed in SEC Form D filings
- GARDINER SMITHExecutive Officer, DirectorNamed in SEC Form D filings
- GERALD W. MCLAUGHLINExecutive Officer, DirectorNamed in SEC Form D filings
Show all 14 people
- JAMES BARRETTDirectorNamed in SEC Form D filings
- Kristin ShermanExecutive OfficerNamed in SEC Form D filings
- Michela GallagherDirector, Executive OfficerNamed in SEC Form D filings
- PATRICK W. LEPOREDirectorNamed in SEC Form D filings
- Robert F. PostlethwaitExecutive Officer, DirectorNamed in SEC Form D filings
- RONALD NORDMANNDirectorNamed in SEC Form D filings
- Timothy F. ParshallExecutive OfficerNamed in SEC Form D filings
- William RingoDirectorNamed in SEC Form D filings
What it has protected
USPTO · 14 granted of 40- New patentBenzazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentUSPTOUS 12,760,030
- GrantedBenzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentUSPTOUS 12,528,819
- GrantedBenzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentUSPTOUS 12,291,535
Show all 40 patent records
- Benzazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentOct 13, 2026 · US 12,760,030Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentJan 20, 2026 · US 12,528,819Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentMay 6, 2025 · US 12,291,535Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentJul 2, 2024 · US 12,024,525Granted
- Benzazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApr 25, 2024 · Application 18235753Pending
- Polymorphs Of A Gabaa ALPHA5 Agonist And Methods Of Using In The Treatment Of Cognitive ImpairmentSep 7, 2023 · Application 18015445Pending
- Combinations Of Gabaa Alpha 5 Agonists And SV2A Inhibitors And Methods Of Using In The Treatment Of Cognitive ImpairmentAug 31, 2023 · Application 18015439Pending
- Extended Release Pharmaceutical Compositions Of LevetiracetamJun 8, 2023 · Application 17858405Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentMar 30, 2023 · Application 17786175Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentNov 22, 2022 · US 11,505,555Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentAug 16, 2022 · US 11,414,425Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApr 26, 2022 · US 11,312,721Granted
- Combinations Of Gabaa Alpha 5 Agonists And SV2A Inhibitors And Methods Of Using In The Treatment Of Cognitive ImpairmentMar 3, 2022 · Application 17372405Pending
- Extended Release Pharmaceutical Compositions Of LevetiracetamNov 11, 2021 · Application 17125737Pending
- Methods And Compositions For Improving Cognitive FunctionNov 2, 2021 · US 11,160,785Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentOct 12, 2021 · US 11,142,529Granted
- Extended Release Pharmaceutical Compositions Of LevetiracetamFeb 23, 2021 · US 10,925,834Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentOct 27, 2020 · US 10,815,242Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentJun 25, 2019 · US 10,329,301Granted
- Extended Release Pharmaceutical Compositions Of LevetiracetamDec 25, 2018 · US 10,159,648Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentJun 21, 2018 · Application 15847906Pending
- Pyridazine Derivatives, Compositions And Methods For Treating Cognitive ImpairmentOct 31, 2017 · US 9,801,879Granted
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication PCTUS2014071644Pending
- Benzazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication PCTUS2023030637Pending
- Methods For Preventing Or Slowing The Progression Of Cognitive Decline Or Impairment In Subjects Displaying Normal Cognitive PerformanceApplication PCTUS2023017348Pending
- Methods For Preventing Or Slowing The Progression Of Cognitive Decline Or Impairment In SubjectsApplication 63439035Pending
- Benzazepine Derivatives, Compositions, And Method For Treating Cognitive ImpairmentApplication 63399509Pending
- POLYMORPHS OF A GABAA a5 AGONIST AND METHODS OF USING IN THE TREATMENT OF COGNITIVE IMPAIRMENTApplication PCTUS2021041179Pending
- Combinations Of Gabaa Alpha 5 Agonists And SV2A Inhibitors And Methods Of Using In The Treatment Of Cognitive ImpairmentApplication PCTUS2021041184Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication PCTUS2020066182Pending
- Polymorphs Of A Gabaa Alpha 5 Agonist And Methods Of Using In The Treatment Of Cognitive ImpairmentApplication 63050642Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication 62950886Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication PCTUS2019038038Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication 62687195Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication PCTUS2016038224Pending
- Extended Release Pharmaceutical Compositions Of LevetiracetamApplication PCTUS2016033567Pending
- Benzodiazepine Derivatives, Compositions, And Methods For Treating Cognitive ImpairmentApplication 62182336Pending
- Methods For Preventing Or Slowing The Progression Of Cognitive Decline Or Impairment In SubjectsApplication PCTUS2024011396Pending
- Methods And Compositions For Improving Cognitive FunctionApplication PCTUS2014029362Pending
- Methods And Compositions For Treating SchizophreniaApplication PCTUS2013069836Pending
Recent research by its founders
- The HOPE4MCI study: A randomized double‐blind assessment of AGB101 for the treatment of MCI due to AD202428 cites
- Positive Allosteric Modulation of GABAA α5 Receptors Improves Memory performance of rats with Conditions of Hippocampal Hyperactivity20240 cites
- Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma202328 cites
Related companies, and why
- Elevian, Inc.Similar federal contract value in Biotech · null in contracts
- Momentum Superior Holdings, Inc.Similar federal contract value in Biotech · null in contracts
- Viridian TherapeuticsSimilar federal contract value in Biotech · null in contracts
- FILAMENTECH. INC.Similar federal contract value in Biotech · null in contracts
- Magnet BiomedicineSimilar federal contract value in Biotech · null in contracts
- GENESEARCH, INC.Similar federal contract value in Biotech · null in contracts
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.
Sources
Federal grants from SBIR/STTR, NIH, NSF and DoD records. Federal contracts from USAspending.gov. Private capital from SEC Form D. Patents from USPTO. Publications from OpenAlex. Regulatory activity from the Federal Register. Press matched on company name.
How to read this page
Figures show associations in public records, not causes or predictions. Nothing here is investment advice. An em-dash means no record was found under this company's name, not that none exists.
Data freshness
SEC Form D filings through . SBIR and STTR awards through .