Aerpio Therapeutics LLC
CINCINNATI, OH · Founded 2011 · CIK 0001538472 · Biotech · Acquired
Monoclonal antibody (ARP-1536) targeting VE-PTP to activate Tie2 pathway for diabetic macular edema treatment
aerpio.com →- Grants
- $657K
- 3 awards
- Sector median: 1
- Raised
- $45M
- 5 Form D · Nov 2016
- 119 months since last filing
- Contracts
- —
- No federal contracts on record
- Patents
- 11
- 3 granted · 8 pending
- Sector median: 2
Capital Timeline
Federal ↑Equity ↓201120122013201420152016201720182019
| Date | Event | Source | Amount |
|---|---|---|---|
| Private capital raised | Form D · SEC | $5,000,000 | |
| Private capital raised | Form D · SEC | $10,000,000 | |
| Private capital raised | Form D · SEC | $22,000,000 | |
| Federal grant | Department of Health and Human Services · Phase I · Small Molecule Inhibitors of VE-PTP to Mitigate Damage by Radiation Therapy | $225,000 | |
| Federal grant | Department of Health and Human Services · Phase I · Small Molecule Inhibitors of VE-PTP to Mitigate Damage by Radiation Therapy | $225,000 | |
| Private capital raised | Form D · SEC | $4,536,531 | |
| Private capital raised | Form D · SEC | $3,469,141 | |
| Federal grant | Department of Health and Human Services · Phase II · Advancing ARP-1536, an Anti-VE-PTP Antibody, as an Adjunctive Therapy for the Treatment of Sight-Threatening Retinopathies | $207,281 |
Federal grant · SBIR/STTRForm D · SEC
Peer position
| # | Company | Contracts | Disclosed equity |
|---|---|---|---|
| 1755 | PROTABIT, LLC | — | — |
| 1756 | LAMNOTHERAPEUTICS, INC. | — | — |
| 1757 | REACTIVE BIOSCIENCES INC | — | $43M |
| 1758 | Aerpio Therapeutics LLC | — | $45M |
| 1759 | SERINA THERAPEUTICS INC | — | $34M |
| 1760 | Iterative Therapeutics Inc. | — | — |
| 1761 | Rhodium Scientific, LLC | — | — |
Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.
Founders & Team
- Reinhard AmbrosDirector
- Anupam DalalDirector
- William DalyExecutive Officer
- Alan FishmanExecutive Officer
- Joseph GardnerDirector · Executive Officer
- Adrienne GravesDirector
- Ian HowesExecutive Officer
- Chau KhuongDirector
- Campbell MurrayDirector
- Duane NashDirector
- Steve PakolaExecutive Officer
- Kevin PetersExecutive Officer
- John RiceDirector
- Muneer SatterDirector
- Robert ShalwitzExecutive Officer
- Lauren SilvermanDirector
- Paul WeissDirector
Patents
- Humanized Monoclonal Antibodies That Target Protein Tyrosine Phosphatase-beta (hptp-beta / Ve-ptp)granted
- Methods Of Treating Ocular Conditions By Administering Humanized Monoclonal Antibodies That Target Ve-ptp (hptp-beta)granted
- Human Protein Tyrosine Phosphatase Inhibitors And Methods Of Usegranted
- Compositions And Methods For Treating Ocular Diseasesapplication
- Compounds, Compositions, And Methods For Preventing Metasasis Of Cancer Cellsapplication
- ANTIBODIES THAT BIND HUMAN PROTEIN TYROSINE PHOSPHATASE beta (HPTPbeta) AND USES THEREOFapplication
- Compositions, Formulations And Methods For Treating Ocular Diseasesapplication
- Compositions, Formulations And Methods For Treating Ocular Diseasesapplication
- Methods For Treating Vascular Leak Syndromeapplication
- Bispecific Antibodies That Target Ve-ptp (hptp-b) And Vegfapplication
- Multispecific Antibodies That Target Hptp-b (ve-ptp) And Vegfapplication
Regulatory activity · Biotech
- New Animal Drugs; Approval of New Animal Drug Applications; Withdrawal of Approval of New Animal Drug Application; Change of SponsorFood and Drug Administration
- Medical Devices; General and Plastic Surgery Devices; Classification of the Skin Patch for Treatment of HyperhidrosisFood and Drug Administration
- Medical Devices; Anesthesiology Devices; Classification of the Monitor for Opioid Induced Impairment of OxygenationFood and Drug Administration
- Medical Devices; Orthopedic Devices; Classification of the Medial Knee Implanted Shock AbsorberFood and Drug Administration
- Medical Devices; Neurological Devices; Classification of the External Lower Extremity Nerve Stimulator for Restless Legs SyndromeFood and Drug Administration
- Medical Devices; General Hospital and Personal Use Devices; Classification of the Infant Supine Sleep SystemFood and Drug Administration
Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.