AcePre, LLC

Columbia, SC · Biotech · Private

Small-molecule therapeutic targeting pyruvate dehydrogenase kinase 1 (PDHK1) to modulate macrophage inflammasome activation and metabolic rewiring in sepsis

Grants
$3.0M
11 awards
Sector median: 1
Raised
—
No Form D on record
Contracts
—
No federal contracts on record
Patents
—
No published records under this name
Sector median: 2

Capital Timeline

Federal above the line · equity below · node area scaled to amount
Capital and federal award history
DateEventSourceAmount
Federal grantDepartment of Health and Human Services · Phase I · Emodin as a complementary dietary therapy to reduce toxicity of 5 fluorouracil$261,212
Federal grantDepartment of Health and Human Services · Phase I · Emodin as a complementary dietary therapy to reduce toxicity of 5 fluorouracil$38,933
Federal grantDepartment of Health and Human Services · Phase I · Development of Dietary Quercetin to Treat Muscle Wasting Disorders$299,998
Federal grantDepartment of Health and Human Services · Phase I · A novel polymer-metal nanocomplex for ovarian cancer treatment$392,803
Federal grantDepartment of Health and Human Services · Phase I · Use novel natural compound Sparstolonin B to treat bacterial sepsis$300,000
Federal grantDepartment of Health and Human Services · Phase I · Development of Dietary Quercetin to Treat Muscle Wasting Disorders$52,000
Federal grantDepartment of Health and Human Services · Phase I · The development of a multifunctional nanoenzyme for AD treatment$299,628
Federal grantDepartment of Health and Human Services · Phase I · Targeting macrophage maladaptation for bacterial sepsis treatment$299,982
Federal grantDepartment of Health and Human Services · Phase I · Targeting macrophage maladaptation for bacterial sepsis treatment$297,328
Federal grantDepartment of Health and Human Services · Phase I · Develop a novel strategy to deliver N-acetylcysteine for AD treatment$499,441
Federal grantDepartment of Health and Human Services · Phase I · Develop natural compound emodin as a novel therapy for calcific aortic valve disease$299,953
Federal grant · SBIR/STTR

Peer position

Biotech · 4373 companies · ranked on federal contract value
Biotech companies ranked by federal contract value
#CompanyContractsDisclosed equity
3204OM THERAPEUTICS INC.——
3205Anaveon——
3206IMETABOLIC BIOPHARMA CORPORATION——
3207AcePre, LLC——
3208CuronBiotech Inc——
3209Gerologix, Inc.——
3210Culture Robotics, Inc——

Ranked on federal contract value rather than capital raised. The equity column is the comparison worth making — companies at the same procurement position often sit at very different points in their funding history.

Regulatory activity · Biotech

Sector-level, not company-level

Rules are matched to sector, not to company. Recent activity in a sector is context rather than a signal about this business — until rules are matched to what a company actually builds, the section is shown as context and nothing more.